Wojtczak Beata, Kaliszewski Krzysztof, Sutkowski Krzysztof, Głód Mateusz, Barczyński Marcin
Department and Clinic of General, Gastroenterological and Endocrine Surgery, Wroclaw Medical University, Wroclaw, Poland.
Department of Endocrine Surgery, Third Chair of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Arch Med Sci. 2018 Mar;14(2):321-328. doi: 10.5114/aoms.2016.63003. Epub 2016 Oct 17.
Paresis of the recurrent laryngeal nerve (RLN) is a complication of thyroid surgery. Neuromonitoring as is gaining acceptance among surgeons. The aim of the study was to assess the number of technical problems in the initial phase of intraoperative neuromonitoring (IONM) use and the specificity, sensitivity, positive predictive value and negative predictive value of neuromonitoring. The number of cases of postoperative paresis (transient and permanent) was assessed.
The prospective analysis included 101 thyroid operations with IONM (190 RLNs at risk of injury) in the period from January to April, 2012. Demographic data, rate of RLN identification, sensitivity, specificity and predictive value of the method, the duration of the procedurę and the percentage of RLN paresis were considered.
The RLN was identified in 92% of the cases. Technical problems were observed in 12.98%, of which 61% were due to incorrect positioning of the endotracheal tube electrodes in relation to the vocal cords. The sensitivity, specificity, negative and positive predictive value and the accuracy of the method were respectively 71%, 98%, 62.5%, 98.9% and 97%. Early nerve injury occurred in 3.7% of the cases; 2.6% were temporary paresis and 1.1% permanent.
During the initial stages of implementing IONM we experienced technical problems that required correction in every tenth patient. The positive predictive value was relatively low; nevertheless, good results in terms of the rate of accurate identification of the RLN as well as the low rate of RLN paresis support the use of this method.
喉返神经麻痹是甲状腺手术的一种并发症。神经监测正逐渐被外科医生所接受。本研究的目的是评估术中神经监测(IONM)使用初期的技术问题数量以及神经监测的特异性、敏感性、阳性预测值和阴性预测值。评估术后麻痹(暂时性和永久性)的病例数量。
前瞻性分析纳入了2012年1月至4月期间101例采用IONM的甲状腺手术(190条喉返神经有损伤风险)。考虑了人口统计学数据、喉返神经识别率、该方法的敏感性、特异性和预测值、手术持续时间以及喉返神经麻痹的百分比。
92%的病例中识别出了喉返神经。观察到12.98%存在技术问题,其中61%是由于气管插管电极相对于声带的位置不正确所致。该方法的敏感性、特异性、阴性和阳性预测值以及准确性分别为71%、98%、62.5%、98.9%和97%。3.7%的病例发生早期神经损伤;2.6%为暂时性麻痹,1.1%为永久性麻痹。
在实施IONM的初期阶段,我们遇到了技术问题,每十名患者中就有一人需要进行纠正。阳性预测值相对较低;然而,在准确识别喉返神经的比率以及较低的喉返神经麻痹发生率方面取得的良好结果支持了该方法的使用。