Kuryga Dorota, Wojskowicz Piotr, Szymczuk Jaroslaw, Wojdyla Anna, Milewska Anna J, Barczynski Marcin, Dadan Jacek, Rogowski Marek, Mysliwiec Piotr
Department of Otolaryngology, Medical University of Bialystok, Bialystok, Poland.
1 Department of General and Endocrinological Surgery, Medical University of Bialystok, Bialystok, Poland.
Arch Med Sci. 2019 Jun 7;17(5):1294-1302. doi: 10.5114/aoms.2019.85737. eCollection 2021.
Even though incidence of recurrent laryngeal nerve palsy (RLNP) is low, it affects importantly the quality of life of patients and remains one of main medicolegal litigation problems in surgery. Intraoperative neuromonitoring (IONM) has become widely accepted tool helping in recurrent laryngeal nerve identification, however no clear association of IONM with RLNP rate has been demonstrated. The aim of our study was to assess whether training in IONM influences rates of RNLP after thyroid surgery as an independent factor.
We analysed retrospectively 1235 patients who underwent thyroidectomy at the 1st Department of General and Endocrine Surgery, Medical University of Bialystok. Possible risk factors for RLNP were evaluated: application or not of IONM, the extent of surgery or thyroid pathology in correlation with surgeons' experience in IONM (trained or untrained).
There were 2351 nerves at risk (NAR) and 39 RNLP were diagnosed after thyroid surgery (1.66%). Surgeons trained in IONM performed 52.2% of all operations (1200 NAR) with 7 RLNP (0.58%), whereas not-trained had 32 RLNP for 1151 NAR (2.8%; p < 0.001). After 182 thyroidectomies (357 NAR) guided by IONM (14.7%) 3 RLNP were observed (0.84%) vs. 36 palsies per 1994 NAR without IONM (1.81%; = 0.189). The highest danger of RLNP was reported after reoperations and the lowest after subtotal thyroidectomies. We found no association between thyroid pathology and RLNP rate.
According to our study training in IONM decreases chances of RLNP especially during total or near total thyroidectomy.
尽管喉返神经麻痹(RLNP)的发生率较低,但它严重影响患者的生活质量,仍是外科手术中主要的医疗法律诉讼问题之一。术中神经监测(IONM)已成为帮助识别喉返神经的广泛接受的工具,然而,IONM与RLNP发生率之间尚无明确关联。我们研究的目的是评估IONM培训作为一个独立因素是否会影响甲状腺手术后RLNP的发生率。
我们回顾性分析了在比亚韦斯托克医科大学第一普通与内分泌外科接受甲状腺切除术的1235例患者。评估了RLNP的可能危险因素:是否应用IONM、手术范围或甲状腺病理情况以及外科医生在IONM方面的经验(受过培训或未受过培训)。
甲状腺手术后有2351条神经处于危险中(NAR),诊断出39例RLNP(1.66%)。接受IONM培训的外科医生进行了所有手术的52.2%(1200例NAR),其中7例RLNP(0.58%),而未受过培训的医生在1151例NAR中有32例RLNP(2.8%;p<0.001)。在IONM引导下进行182例甲状腺切除术后(357例NAR)(占14.7%),观察到3例RLNP(0.84%),而未使用IONM的1994例NAR中有36例麻痹(1.81%;p = 0.189)。再次手术后RLNP的风险最高,次全甲状腺切除术后风险最低。我们发现甲状腺病理情况与RLNP发生率之间无关联。
根据我们的研究,IONM培训可降低RLNP的发生几率,尤其是在全甲状腺切除或近全甲状腺切除术中。