Miller R M, Taylor D E, Ringrose B S
Department of Applied Physiology and Surgical Sciences, Royal College of Surgeons of England, London.
Life Support Syst. 1985;3 Suppl 1:466-70.
A polyester/acrylic acid copolymer was compared with unmodified polyester as control. These were implanted as an aorto-aortic bypass graft, in 18 dogs, for periods ranging from 3 to 17 months. The copolymer had a smaller rise in circumferential elastance, a significantly slower pulse wave velocity, and a markedly lower longitudinal impedance. In addition, it had a more organised and significantly thinner pseudointima. We conclude, therefore, that copolymerization produced improved haemodynamic results and surface properties which appeared to discourage fibrin and platelet adherence. We anticipate that this type of prosthesis could be expected to produce better long term results than those polyester prostheses at present available.
将一种聚酯/丙烯酸共聚物与未改性的聚酯作为对照进行比较。将它们作为主动脉-主动脉旁路移植物植入18只狗体内，植入时间为3至17个月。该共聚物的周向弹性增加较小，脉搏波速度明显较慢，纵向阻抗明显较低。此外，它具有更有序且明显更薄的假内膜。因此，我们得出结论，共聚产生了改善的血流动力学结果和表面特性，这似乎抑制了纤维蛋白和血小板的黏附。我们预计，这种类型的假体有望产生比目前可用的聚酯假体更好的长期效果。
