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早产儿的肠壁积气:我们应该将所有肠壁积气都视为坏死性小肠结肠炎来治疗吗?

Pneumatosis intestinalis in a preterm infant: should we treat all intestinal pneumatosis as necrotising enterocolitis?

作者信息

Chew Siu Jun, Victor Rajadurai Samuel, Gopagondanahalli Krishna Revanna, Chandran Suresh

机构信息

Department of Neonatology, KK Women's and Children's Hospital, Singapore.

Duke NUS Medical School, Singapore.

出版信息

BMJ Case Rep. 2018 Mar 28;2018:bcr-2018-224356. doi: 10.1136/bcr-2018-224356.

DOI:10.1136/bcr-2018-224356
PMID:29599384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5878242/
Abstract

Gastric pneumatosisis a very rare site of pneumatosis intestinalis (PI), and we report this finding in a preterm female infant with cyanotic congenital heart disease. The infant was stable initially on nasal intermittent mandatory ventilation; however, torrential pulmonary flow through a large patent ductus arteriosus prompted closure using oral ibuprofen. After an episode of haematochezia, she developed PI, affecting mainly the gastric wall and small intestine with portal venous gas. Her bowel movements were regular, with no abdominal distension or significant gastric aspirates. She was haemodynamically stable with negative infective markers. Management consisted of endotracheal intubation and ventilation, gastric decompression and broad-spectrum antibiotics. Both the gastric and intestinal pneumatosis resolved within 24 hours and she made an uneventful recovery. If PI is not due to necrotising enterocolitis, enteral nutrition can be initiated early and prolonged course of broad-spectrum antibiotics could have been avoided.

摘要

胃壁积气是肠壁积气(PI)非常罕见的部位,我们报告了一名患有青紫型先天性心脏病的早产女婴出现这一情况。该婴儿最初通过鼻间歇强制通气情况稳定;然而,经大型动脉导管未闭的大量肺血流促使使用口服布洛芬进行封堵。在一次便血发作后,她出现了PI,主要累及胃壁和小肠并伴有门静脉积气。她的排便规律,无腹胀或大量胃内容物吸出。她血流动力学稳定,感染指标为阴性。治疗包括气管插管和通气、胃减压及广谱抗生素治疗。胃壁和肠壁积气在24小时内均消失,她顺利康复。如果PI不是由坏死性小肠结肠炎引起,可早期开始肠内营养,避免使用延长疗程的广谱抗生素。

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本文引用的文献

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Gastric emphysema a spectrum of pneumatosis intestinalis: a case report and literature review.胃气肿——一种肠壁囊样积气症:病例报告及文献综述
Case Rep Gastrointest Med. 2014;2014:891360. doi: 10.1155/2014/891360. Epub 2014 Jul 1.
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Gastric pneumatosis in a premature neonate.一名早产儿的胃壁积气
AJP Rep. 2011 Sep;1(1):11-4. doi: 10.1055/s-0030-1271218. Epub 2011 Jan 24.
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The pathophysiology of non-steroidal anti-inflammatory drug (NSAID)-induced mucosal injuries in stomach and small intestine.非甾体抗炎药(NSAID)诱导的胃和小肠黏膜损伤的病理生理学。
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Hepatic portal venous gas: physiopathology, etiology, prognosis and treatment.肝门静脉积气:病理生理学、病因、预后及治疗
World J Gastroenterol. 2009 Aug 7;15(29):3585-90. doi: 10.3748/wjg.15.3585.
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Gastric pneumatosis and portal venous gas: benign findings in hypertrophic pyloric stenosis.胃壁积气和门静脉积气:肥厚性幽门狭窄的良性表现。
Pediatr Radiol. 2009 Apr;39(4):413. doi: 10.1007/s00247-008-1088-2. Epub 2009 Jan 9.
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Gastroduodenal emphysema.胃十二指肠气肿
J Pediatr Surg. 2008 Nov;43(11):2121-3. doi: 10.1016/j.jpedsurg.2008.07.019.
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Gastric pneumatosis intestinalis: an indicator of intestinal perforation in preterm infants with necrotizing enterocolitis?胃壁积气:坏死性小肠结肠炎早产儿肠穿孔的一个指标?
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8
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10
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