Gupta Damini, Bhandari Aditya Bikram, Dorfman Kevin D
Department of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Macromolecules. 2018 Mar 13;51(5):1748-1755. doi: 10.1021/acs.macromol.7b02270. Epub 2018 Feb 20.
We have measured the diffusivity of λ-DNA molecules in approximately square nanochannels with effective sizes ranging from 117 nm to 260 nm at moderate ionic strength. The experimental results do not agree with the non-draining scaling predicted by blob theory. Rather, the data are consistent with the predictions of previous simulations of the Kirkwood diffusivity of a discrete wormlike chain model, without the need for any fitting parameters.
我们在中等离子强度下，测量了λ-DNA分子在有效尺寸范围从117纳米至260纳米的近似方形纳米通道中的扩散系数。实验结果与斑点理论预测的非排水标度不符。相反，这些数据与之前关于离散蠕虫状链模型的柯克伍德扩散系数模拟的预测结果一致，无需任何拟合参数。
