表面活性蛋白 A、B、C 和 D 在婴儿唇腺和黏膜中的免疫定位。
Immunolocalization of Surfactant Proteins SP-A, SP-B, SP-C, and SP-D in Infantile Labial Glands and Mucosa.
机构信息
Department of Oral and Maxillofacial Surgery, Technical University of Munich, Munich, Germany.
Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
出版信息
J Histochem Cytochem. 2018 Jul;66(7):531-538. doi: 10.1369/0022155418766063. Epub 2018 Mar 30.
Abstract
Surfactant proteins in different glandular structures of the oral cavity display antimicrobial activity for protection of invading microorganisms. Moreover, they are involved in lowering liquid tension in fluids and facilitate secretion flows. Numerous investigations for studying the occurrence of surfactant proteins in glandular tissues were performed using different methods. In the oral cavity, minor salivary glands secrete saliva continuously for the maintenance of a healthy oral environment. For the first time, we could show that infantile labial glands show expression of the surfactant proteins (SP) SP-A, SP-B, SP-C, and SP-D in acinar cells and the duct system in different intensities. The stratified squamous epithelium of the oral mucosa revealed positive staining for SPs in various cell layers.
摘要
口腔不同腺体结构中的表面活性剂蛋白具有抗微生物活性，可保护入侵的微生物。此外，它们还参与降低液体的表面张力并促进分泌液流动。为了研究表面活性剂蛋白在腺体组织中的存在，人们使用了不同的方法进行了大量的研究。在口腔中，小唾液腺持续分泌唾液以维持健康的口腔环境。我们首次发现，婴儿唇腺的腺泡细胞和导管系统中均有不同强度的表面活性剂蛋白（SP）SP-A、SP-B、SP-C 和 SP-D 的表达。口腔黏膜的复层鳞状上皮在不同细胞层中均对 SP 呈阳性染色。
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