Avian Diseases Laboratory, College of Veterinary Medicine, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
Avian Diseases Laboratory, College of Veterinary Medicine, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
Infect Genet Evol. 2018 Jul;61:127-133. doi: 10.1016/j.meegid.2018.03.025. Epub 2018 Mar 27.
In recent years, avian paramyxovirus type 4 (APMV-4) frequently isolated from wild and domestic bird populations particularly waterfowls worldwide. However, molecular characteristics and genetic diversity of APMV-4 are uncertain, owing to the limited availability of sequence information. A total of 11 APMV-4 strains from 9850 fecal, swab, and environmental samples were isolated during the surveillance program in wintering seasons of 2013-2017 in South Korea. We performed genetic characterization and phylogenetic analysis to investigate the genetic diversity and relatedness between isolates from the region. We report high APMV-4 genetic diversity (multiple genotypes and sub-genotypes) among wild bird and poultry populations in Korea and that the potential virus exchange occurs between neighboring countries via wild bird migration. Furthermore, our study results suggest the possibility of transcontinental transmission of APMV-4 between Asia and Europe.
近年来，禽副黏病毒 4 型（APMV-4）频繁从世界范围内的野生和家养鸟类，尤其是水禽中分离出来。然而，由于序列信息有限，APMV-4 的分子特征和遗传多样性尚不确定。在韩国越冬季节的 2013-2017 年监测计划中，从 9850 份粪便、拭子和环境样本中总共分离出 11 株 APMV-4 株。我们进行了遗传特征分析和系统发育分析，以调查该地区分离株之间的遗传多样性和相关性。我们报告了韩国野生鸟类和家禽群体中 APMV-4 的高遗传多样性（多种基因型和亚型），并且通过野生鸟类迁徙，邻国之间存在潜在的病毒交换。此外，我们的研究结果表明，APMV-4 可能在亚洲和欧洲之间发生跨大陆传播。
