Vickers Kayci L, Breslin Kathleen, Roalf David R, Kamath Vidyulata, Xie Sharon X, Moberg Paul J, Wolk David A, Mechanic-Hamilton Dawn
Alzheimer's Disease Center, Department of Neurology, Perelman School of Medicine, Philadelphia, PA, USA.
Department of Psychology, Drexel University, Philadelphia, PA, USA.
Arch Clin Neuropsychol. 2019 Mar 1;34(2):254-258. doi: 10.1093/arclin/acy021.
The current study establishes normative Sniffin' Sticks Odor Identification Test (SS-OIT) scores for cognitively intact older adults.
Two hundred and twenty-six cognitively normal older adults were identified as eligible for the current study (Mean Age = 70.49 years; 71.7% female). Important demographic covariates were identified using step-wise regression, and a normative regression equation was developed.
Analyses of the effects of demographic variables (including age, education, and sex) on SS-OIT performance revealed that age was the only significant predictor, b = -0.07, SEb = .01, p < .01. A final regression equation was determined and normative data are reported in 5-year increments for a number of percentile ranks.
Normative performance on the SS-OIT for adults over the age of 50 was established in a large and demographically diverse sample. These data are needed in order for clinicians to be able to include olfactory testing, a sensitive marker of neurodegeneration, in their assessment armamentarium.
本研究为认知功能正常的老年人建立了标准化的嗅觉棒气味识别测试（SS-OIT）分数。
226名认知正常的老年人被确定符合本研究条件（平均年龄 = 70.49岁；71.7%为女性）。使用逐步回归确定重要的人口统计学协变量，并建立了标准化回归方程。
对人口统计学变量（包括年龄、教育程度和性别）对SS-OIT表现的影响进行分析后发现，年龄是唯一显著的预测因素，b = -0.07，SEb = 0.01，p < 0.01。确定了最终回归方程，并按5年增量报告了多个百分位数的标准化数据。
在一个规模大且人口统计学特征多样的样本中建立了50岁以上成年人SS-OIT的标准化表现。临床医生需要这些数据，以便能够将嗅觉测试（神经退行性变的敏感标志物）纳入其评估手段中。
