Hsieh Ching-Hung, Chen Philip G, Zhou Bing, Lin Li-Jung, Lai Jen-Tsung, Shen Ping-Hung
Department of Otolaryngology, Kuang Tien General Hospital, Taichung.
Department of Otolaryngology-Head and Neck Surgery, University of Texas Health San Antonio, San Antonio, Texas.
Allergy Rhinol (Providence). 2021 Feb 15;12:2152656721991525. doi: 10.1177/2152656721991525. eCollection 2021 Jan-Dec.
The Taiwan Smell Identification Test (TWSIT) was developed and successfully administered in Taiwanese population since 2015. However, for sanitation reason, the original liquid-jar form of this test is not appropriate. The commercialized TWSIT was then re-designed as "scratch-and-sniff" version: the TIBSIT (Top International Biotech, Taipei, Taiwan). This project aims to investigate the normative value of TIBSIT in different age groups and genders.
Volunteers aged 20 to 80 with no subjective smell loss were recruited in a rhinology clinic. The participants were given full instructions on using the TIBSIT.
Two hundred and nine healthy subjects (female: male =107: 102) were enrolled into this study. The median TIBSIT score in female and male subjects is 47 and 46, respectively. Subjects were further divided into three age groups: (A) 20∼34 years (n = 77), (B) 35∼54 years (n = 77), and (C) 55∼80 years (n = 55). The TIBSIT scores at the tenth percentile value at each age group of male patients are 43, 42 and 37; while the scores at the tenth percentile value at each age group of female patients are 42, 42 and 41. TIBSIT score was significantly and inversely correlated with age (Spearman rho = - 0.20, = 0.004.).
We established the normative values of the new TIBSIT in different age groups in Taiwan. Future nation-wide screening is needed for more sophisticated norms establishment.
台湾嗅觉识别测试（TWSIT）自2015年起在台湾人群中开发并成功实施。然而，出于卫生原因，该测试最初的液体罐形式并不合适。商业化的TWSIT随后被重新设计为“刮擦嗅闻”版本：即TIBSIT（台湾台北国际生物技术公司）。本项目旨在研究TIBSIT在不同年龄组和性别的正常参考值。
在一家鼻科诊所招募了20至80岁无主观嗅觉减退的志愿者。向参与者提供了使用TIBSIT的完整说明。
本研究共纳入209名健康受试者（女性：男性 = 107:102）。女性和男性受试者的TIBSIT评分中位数分别为47分和46分。受试者进一步分为三个年龄组：（A）20∼34岁（n = 77），（B）35∼54岁（n = 77），和（C）55∼80岁（n = 55）。男性患者各年龄组第十百分位数的TIBSIT评分分别为43、42和37；而女性患者各年龄组第十百分位数的评分分别为42、42和41。TIBSIT评分与年龄呈显著负相关（斯皮尔曼相关系数rho = -0.20，P = 0.004）。
我们建立了台湾不同年龄组新TIBSIT的正常参考值。未来需要进行全国范围的筛查以建立更完善的标准。
