Wang R, Tang Z, Sun F, Diao L J
Beijing Geriatric Healthcare Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China; Department of Geriatrics, Qingdao 8th People's Hospital, Qingdao 266000, China.
Beijing Geriatric Healthcare Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Mar 10;39(3):286-288. doi: 10.3760/cma.j.issn.0254-6450.2018.03.007.
To investigate the prevalence of hyperuricemia (HUA) in the elderly in China. A randomized stratified cluster sampling survey was conducted. And 5 376 residents aged ≥60 year in 7 Beijing, Xi'an and Harbin in northern China and Chengdu, Chongqing, Changsha and Shanghai in southern China were surveyed. A unified questionnaire was used to collect their basic information, and blood samples were taken from them to detect the level of plasma uric acid (UA). The differences in hyperuricemia prevalence among different groups were compared with (2) test. The mean concentration of plasma UA was 302.8 μmol/L in the elderly surveyed, 329.5 μmol/L in males and 282.7 μmol/L in females, 272.4 μmol/L in rural residents and 315.5 μmol/L in urban residents. Our study showed the prevalence of hyperuricemia was 13.1% in the elderly surveyed. The prevalence of hyperuricemia in women (14.1%) was higher than that in men (12.0%) (<0.05); and the prevalence of hyperuricemia was higher in urban residents (15.8%) than in rural residents (6.9%) (<0.01); in southern area (16.0%) than in northern area (11.6%) (<0.01). Both the plasma UA level and the prevalence of hyperuricemia increased with age in those aged ≥60 years. The average prevalence of hyperuricemia were 9.5%, 11.9%, 14.5%, 16.4% and 21.9% and the plasma UA levels were 287.7, 295.9, 308.1, 311.6 and 323.3 μmol/L respectively in age group ≥60, 65, 70, 75 and 80 years (<0.01). The result showed that mean concentration of plasma UA was 302.8 μmol/L and the overall prevalence of hyperuricemia was 13.1% in the elderly surveyed in China. The prevalence of hyperuricemia in females was higher than in males, in urban residents than in rural residents and in southern area than in northern area. Both the UA level and prevalence of hyperuricemia increased with age.
为调查中国老年人高尿酸血症（HUA）的患病率，开展了一项随机分层整群抽样调查。对中国北方北京、西安和哈尔滨以及南方成都、重庆、长沙和上海7个城市的5376名年龄≥60岁的居民进行了调查。采用统一问卷收集其基本信息，并采集血样检测血浆尿酸（UA）水平。不同组间高尿酸血症患病率的差异采用（2）检验进行比较。接受调查的老年人血浆UA平均浓度为302.8μmol/L，男性为329.5μmol/L，女性为282.7μmol/L，农村居民为272.4μmol/L，城市居民为315.5μmol/L。我们的研究显示，接受调查的老年人中高尿酸血症患病率为13.1%。女性高尿酸血症患病率（14.1%）高于男性（12.0%）（<0.05）；城市居民高尿酸血症患病率（15.8%）高于农村居民（6.9%）（<0.01）；南方地区（16.0%）高于北方地区（11.6%）（<0.01）。在≥60岁人群中，血浆UA水平和高尿酸血症患病率均随年龄增长而升高。年龄≥60岁、65岁、70岁、75岁和80岁组的高尿酸血症平均患病率分别为9.5%、11.9%、14.5%、16.4%和21.9%，血浆UA水平分别为287.7、295.9、308.1、311.6和323.3μmol/L（<0.01）。结果显示，中国接受调查的老年人血浆UA平均浓度为3.8μmol/L，高尿酸血症总体患病率为13.1%。女性高尿酸血症患病率高于男性，城市居民高于农村居民，南方地区高于北方地区。UA水平和高尿酸血症患病率均随年龄增长而升高。
