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治疗达标——银屑病的一个现实目标?

Treating to Target-A Realistic Goal in Psoriasis?

作者信息

Gordon Kenneth B, Armstrong April W, Menter M Alan, Wu Jashin J

机构信息

Professor and Chair Department of Dermatology Medical College of Wisconsin Milwaukee, Wisconsin.

Associate Professor of Clinical Dermatology Associate Dean for Clinical Research Keck School of Medicine of the University of Southern California Los Angeles, California.

出版信息

Semin Cutan Med Surg. 2018 Feb;37(2S):S44-S47. doi: 10.12788/j.sder.2018.010.

Abstract

For many patients, the new biologic therapies for psoriasis can improve Psoriasis Area and Severity Index (PASI) scores in a relatively short time. But when results are less than optimal, patients often become frustrated. By providing effective medical treatment using a treat-to-target strategy, clinicians can relieve symptoms and halt disease progression. Although body surface area (BSA) and PASI scores are appropriate for analyzing results of clinical trials, clinicians need to use more patient-centered assessments of patients' progress such as the Dermatology Life Quality Index (DLQI) and Psoriasis Symptom Inventory (PSI), as well as other validated patientreported outcomes, which can enable them to set realistic and achievable goals for individual patients. Semin Cutan Med Surg 37(supp2):S44-S47.

摘要

对于许多患者而言,新型银屑病生物疗法可在相对较短的时间内改善银屑病面积和严重程度指数(PASI)评分。但当效果不尽如人意时,患者往往会感到沮丧。通过采用达标治疗策略提供有效的医学治疗,临床医生可以缓解症状并阻止疾病进展。虽然体表面积(BSA)和PASI评分适用于分析临床试验结果,但临床医生需要使用更多以患者为中心的评估方法来评估患者的病情进展,如皮肤病生活质量指数(DLQI)和银屑病症状量表(PSI),以及其他经过验证的患者报告结局,这可以使他们为个体患者设定现实且可实现的目标。《皮肤外科医学杂志》37(增刊2):S44 - S47。

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