Faculty of Public Health, Mahidol University, Bangkok 10400, Thailand.
Department of Environmental, Occupational and Geospatial Health Sciences, CUNY Institute for Implementation Sciences in Population Health, CUNY Graduate School of Public Health and Health Policy, New York, NY 10027, USA.
Int J Environ Res Public Health. 2018 Apr 2;15(4):659. doi: 10.3390/ijerph15040659.
As an intermediate endpoint to cardiovascular disease, arterial stiffness has received much attention recently. So far, the research on work stress and arterial stiffness is still sparse and inconsistent, and no investigations on work stress and cardiovascular health among the Thai working population have been reported. Therefore, we conducted an epidemiological study among 2141 Thai enterprise employees (858 men and 1283 women) who were free from any diagnosed cardiovascular disease. Work stress was measured using Karasek's Job Demand-Control model for job strain (a combination of high demand and low control). Arterial stiffness was evaluated by a non-invasive approach using pulse-wave analysis based on a finger photoplethysmogram. Multivariable linear regression was applied to examine associations between job strain and arterial stiffness. In men, job strain was significantly associated with arterial stiffness (β = 0.078, 95% confidence interval = 0.026 to 0.130), after accounting for sociodemographic, behavioral, dietary and biomedical factors. However, the association in women was not significant. As the first study in Thailand on work stress and cardiovascular risk, we found that job strain might be an important risk factor for cardiovascular disease among Thai working men. Further studies with longitudinal design are warranted.
作为心血管疾病的中间终点，动脉僵硬最近受到了广泛关注。到目前为止，关于工作压力与动脉僵硬的研究仍然很少且不一致，并且尚未有关于泰国工作人群的工作压力与心血管健康的研究报告。因此，我们在 2141 名没有任何确诊心血管疾病的泰国企业员工（858 名男性和 1283 名女性）中进行了一项流行病学研究。工作压力使用 Karasek 的工作需求-控制模型进行评估，该模型用于衡量工作紧张程度（高需求与低控制的结合）。动脉僵硬通过基于手指光体积描记法的脉搏波分析进行非侵入性评估。多变量线性回归用于检查工作紧张程度与动脉僵硬之间的关联。在男性中，在考虑了社会人口统计学、行为、饮食和生物医学因素后，工作紧张程度与动脉僵硬显著相关（β=0.078，95%置信区间为 0.026 至 0.130）。然而，女性的相关性不显著。作为泰国关于工作压力与心血管风险的第一项研究，我们发现工作紧张程度可能是泰国男性患心血管疾病的一个重要危险因素。需要进一步进行具有纵向设计的研究。
