Townsend Raymond R
Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., USA.
Pulse (Basel). 2017 Jan;4(Suppl 1):3-7. doi: 10.1159/000448454. Epub 2016 Dec 23.
The use of arterial stiffness measurements in longitudinal cohorts of normal populations, hypertensive patients, diabetic patients, healthy elderly, and patients on hemodialysis have confirmed the value of this important measure of arterial health, and established its complementary role to measures of blood pressure. Its contribution to understanding cardiovascular and mortality risk beyond blood pressure measurements has moved measures of arterial stiffness into the ranks of factors such as elevated cholesterol, diabetes, and left ventricular hypertrophy in considering cardiovascular risk. The recent international collaboration's publication of reference ranges for normal people and those with hypertension, along with the American Heart Association's recent scientific statement on standardizing arterial stiffness measurements are important aspects to consider in future studies employing these valuable methods, particularly as interventions that not only lower blood pressure but improve arterial function are tested in the clinical arena.
在正常人群、高血压患者、糖尿病患者、健康老年人以及血液透析患者的纵向队列中使用动脉僵硬度测量,已证实了这一动脉健康重要指标的价值,并确立了其相对于血压测量指标的补充作用。它在理解超出血压测量范畴的心血管和死亡风险方面所做的贡献,已使动脉僵硬度测量在考虑心血管风险时跻身于诸如高胆固醇、糖尿病和左心室肥厚等因素之列。近期国际合作发表的正常人和高血压患者的参考范围,以及美国心脏协会最近关于标准化动脉僵硬度测量的科学声明,是未来采用这些有价值方法的研究中需要考虑的重要方面,特别是在临床领域测试不仅能降低血压而且能改善动脉功能的干预措施时。