Brady Paul J, Hayes Martina, McCreary Christine E, O'Halloran Ken D, Giovannitti Joseph A
SAAD Dig. 2017 Jan;33:3-6.
Capnography monitoring during conscious sedation is not currently required for dentistry in Britain and Ireland. Other countries have introduced guidelines and standards requiring capnography monitoring for procedural sedation. This review highlights the variability of procedural sedation including the setting, the position on the sedation continuum, and the routine use of supplemental oxygen. Specific research is required for conscious sedation in a dental setting to support standards and guidelines with regard to capnography monitoring. The Academy of Medical Royal Colleges and their Faculties emphasise that each specialty must produce its own guidance for the use of sedative techniques.1 Clinical practice guidelines for the monitoring and safe practice of sedation vary by specialty and institution. Standards are generally set from the best available evidence based research. There is a growing body of literature that recognises the potential additional value of capnography (ETCO2) monitoring during procedural sedation in different settings and for different sedation techniques.2-5 In these studies, capnography reduced the incidence of hypoxaemia during procedural sedation. A meta-analysis published by Waugh et al. (2010) concluded that end-tidal carbon dioxide monitoring is an important addition in detecting respiratory depression during procedural sedation.6 A more recent systematic review by Conway et al. (2016) concluded that patients monitored with capnography in addition to standard monitoring had a reduced risk of hypoxaemia compared to those with only standard monitoring.7 However, it has to be noted that both the Waugh and Conway reviews contained substantial statistical heterogenicity which is likely to affect the quality of the evidence. As research evidence for capnography monitoring from the medical settings studied became available, new standards for capnography monitoring were introduced in several countries (Table 1).
在英国和爱尔兰,目前牙科清醒镇静期间不需要进行二氧化碳监测。其他国家已出台指南和标准,要求在程序镇静期间进行二氧化碳监测。本综述强调了程序镇静的变异性,包括环境、镇静连续体上的位置以及补充氧气的常规使用。牙科环境中清醒镇静需要进行具体研究,以支持关于二氧化碳监测的标准和指南。皇家医学院及其学院强调,每个专业必须制定自己关于镇静技术使用的指南。1 镇静监测和安全操作的临床实践指南因专业和机构而异。标准通常根据现有最佳证据研究制定。越来越多的文献认识到,在不同环境和不同镇静技术的程序镇静期间,二氧化碳监测(呼气末二氧化碳)具有潜在的附加价值。2 - 5 在这些研究中,二氧化碳监测降低了程序镇静期间低氧血症的发生率。Waugh 等人(2010 年)发表的一项荟萃分析得出结论,呼气末二氧化碳监测是检测程序镇静期间呼吸抑制的重要补充。6 Conway 等人(2016 年)最近的一项系统综述得出结论,与仅进行标准监测的患者相比,除标准监测外还进行二氧化碳监测的患者低氧血症风险降低。7 然而,必须指出的是,Waugh 和 Conway 的综述都存在大量统计异质性,这可能会影响证据质量。随着从所研究的医疗环境中获得二氧化碳监测的研究证据,几个国家引入了新的二氧化碳监测标准(表 1)。