Yoshimizu N
Department of Orthopaedic Surgery, School of Medicine, Kanazawa University, Ishikawa, Japan.
Nihon Seikeigeka Gakkai Zasshi. 1987 Jul;61(7):943-57.
There are two problems in clinical application of the blood flow measurement by the electrochemically generated hydrogen method: one is to determine the diffusion transport value (DTV) in the absence of blood flow; the other is the variability of DTV among the individual electrodes. In order to solve these problems, I developed a technique to estimate DTV in vivo based on the DTV measured in in vitro experiments. Significant correlation between the DTV of human bone marrow without blood flow (y) and the DTV in 0.5% agar gel dissolved in physiological saline at 0 degrees C (x) was obtained: y = 0.980x + 0.494, r = 0.984, p less than 0.005. It is therefore possible to determine DTV in human bone marrow without blood flow from the DTV measured in vitro. The present technique to estimate DTV in bone marrow via DTV measured in vitro is useful clinically in monitoring blood flow of free vascularized bone graft and of femoral head after fracture-dislocation of the hip.
一是在无血流情况下确定扩散传输值（DTV）；另一个是各个电极之间DTV的变异性。为了解决这些问题，我开发了一种基于体外实验测量的DTV来体内估计DTV的技术。获得了无血流的人骨髓DTV（y）与0℃溶解于生理盐水中的0.5%琼脂凝胶中的DTV（x）之间的显著相关性：y = 0.980x + 0.494，r = 0.984，p < 0.005。因此，有可能根据体外测量的DTV来确定无血流的人骨髓中的DTV。目前通过体外测量的DTV来估计骨髓中DTV的技术在临床上对于监测游离带血管骨移植和髋部骨折脱位后股骨头的血流是有用的。
