用于诊断波斯患者阻塞性睡眠呼吸暂停的柏林问卷、STOP-Bang问卷和爱泼华嗜睡量表的比较
Comparison of Berlin Questionnaire, STOP-Bang, and Epworth Sleepiness Scale for Diagnosing Obstructive Sleep Apnea in Persian Patients.
作者信息
Amra Babak, Javani Maedeh, Soltaninejad Forogh, Penzel Thomas, Fietze Ingo, Schoebel Christoph, Farajzadegan Ziba
机构信息
Department of Medicine, Pulmonary Unit, Isfahan University of Medical Sciences, Bamdad Respiratory Research Center, Isfahan, Iran.
Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Int J Prev Med. 2018 Mar 9;9:28. doi: 10.4103/ijpvm.IJPVM_131_17. eCollection 2018.
BACKGROUND
Obstructive sleep apnea (OSA) is a common disorder characterized by snoring, daytime sleepiness, fatigue, and repeated termination of airflow (apnea). Standard polysomnography (PSG) is diagnostic gold standard for OSA. PSG is expensive and not available everywhere. To identify the best OSA questionnaire for screening in Persian population, we compared Berlin, STOP-BANG, and Epworth Sleepiness Scale (ESS).
METHODS
In a cross-sectional study conducted on 400 adult patients suspected of OSA in Bamdad Respiratory Research Center, patients completed three questionnaires. For each questionnaire, patients were divided into high risk and low risk. Then, PSG was performed for all patients. According to PSG, patients categorized into without OSA (apnea-hypopnea index [AHI] <5), mild OSA (15> AHI ≥5), moderate OSA (30> AHI ≥15), and severe OSA (AHI ≥30). Based on questionnaires and PSG results, predictive parameters for screening tests were calculated.
RESULTS
There were 234 (58.5%) males and 166 (41.5%) females in study population. Mean age of patients was 49.29 ± 9.75 standard deviation years. There was significant association between age with OSA ( = 0.005) and between body mass index (BMI) and neck circumference, with moderate and severe OSA ( < 0.001). Sensitivities of Berlin, STOP-BANG, and ESS were 86.42%, 81.46%, and 59%, respectively. Specificities of Berlin, STOP-BANG, and ESS were 52.94%, 82.35%, and 76.47%, respectively.
CONCLUSIONS
This study suggested that Berlin and STOP-BANG are more sensitive and accurate than ESS for OSA screening in Iran.
背景
阻塞性睡眠呼吸暂停（OSA）是一种常见疾病，其特征为打鼾、日间嗜睡、疲劳以及气流反复中断（呼吸暂停）。标准多导睡眠图（PSG）是OSA的诊断金标准。PSG价格昂贵且并非在所有地方都可进行。为了确定用于波斯人群筛查的最佳OSA问卷，我们比较了柏林问卷、STOP - BANG问卷和爱泼华嗜睡量表（ESS）。
方法
在巴姆达德呼吸研究中心对400名疑似OSA的成年患者进行的一项横断面研究中，患者完成了三份问卷。对于每份问卷，患者被分为高风险和低风险。然后，对所有患者进行PSG检查。根据PSG结果，患者被分为无OSA（呼吸暂停低通气指数[AHI]<5）、轻度OSA（15>AHI≥5）、中度OSA（30>AHI≥15）和重度OSA（AHI≥30）。根据问卷和PSG结果，计算筛查试验的预测参数。
结果
研究人群中有234名（58.5%）男性和166名（41.5%）女性。患者的平均年龄为49.29±9.75标准差岁。年龄与OSA之间存在显著关联（=0.005），体重指数（BMI）和颈围与中度和重度OSA之间存在显著关联（<0.001）。柏林问卷、STOP - BANG问卷和ESS的敏感性分别为86.42%、81.46%和59%。柏林问卷、STOP - BANG问卷和ESS的特异性分别为52.94%、82.35%和76.47%。
结论
本研究表明，在伊朗，对于OSA筛查，柏林问卷和STOP - BANG问卷比ESS更敏感、更准确。
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