Alsaadi Taoufik, Hammasi Khadija El, Shahrour Tarek M, Shakra Mustafa, Turkawi Lamya, Nasreddine Wassim, Kassie Seada, Raoof Mufeed
American Center for Psychiatry and Neurology, Abu Dhabi.
Department of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi.
Neurol Int. 2017 Dec 11;9(4):7343. doi: 10.4081/ni.2017.7343.
To study the impact of depression and anxiety on health-related quality of life (HRQOL) in patients with multiple sclerosis (pwMS) in the UAE. All consecutive patients attending the MS clinic over a fourmonth period, October 2014 through February 2015, at Sheikh Khalifa Medical city (SKMC) were asked to complete The World Health Organization quality of life abbreviated scale (WHOQOL-BREF), the Patient Health Questionnaire nine-item (PHQ-9) depression scale, and Generalized Anxiety Disorder seven-item (GAD-7) scale. These last two scales were used to screen for depression and anxiety disorders respectively. The study looked at significant variables associated with HRQOL, using multivariate analysis. Eighty patients were enrolled in the study. Both anxiety and depression had a strong positive correlation with HRQOL in univariate analysis. However, depression was the strongest predictor of HRQOL in the patients using linear multi-regression analysis. Screening and timely treatment of both anxiety and depression in MS patients should be a recommended policy when managing pwMS to improve their optimal care and ensure better quality of life.
研究阿联酋多发性硬化症患者（pwMS）中抑郁和焦虑对健康相关生活质量（HRQOL）的影响。2014年10月至2015年2月期间，在谢赫·哈利法医疗城（SKMC）连续四个月到多发性硬化症诊所就诊的所有患者均被要求完成世界卫生组织生活质量简表（WHOQOL-BREF）、患者健康问卷九项（PHQ-9）抑郁量表和广泛性焦虑症七项（GAD-7）量表。后两个量表分别用于筛查抑郁和焦虑症。该研究使用多变量分析，观察与健康相关生活质量相关的显著变量。80名患者参与了该研究。在单变量分析中，焦虑和抑郁与健康相关生活质量均呈强正相关。然而，在使用线性多元回归分析的患者中，抑郁是健康相关生活质量的最强预测因素。在管理多发性硬化症患者以改善其最佳护理并确保更好的生活质量时，对多发性硬化症患者的焦虑和抑郁进行筛查和及时治疗应是一项推荐政策。
