Mochizuki Hitoshi, Ishii Nobuyuki, Shiomi Kazutaka, Nakazato Masamitsu
Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, University of Miyazaki, Japan.
Neurol Int. 2017 Dec 11;9(4):7356. doi: 10.4081/ni.2017.7356.
We investigated the relation between clinical features and electrocardiogram (ECG) parameters in patients with Parkinson's disease (PD). One hundred and fifty-six PD patients were enrolled. Their clinical features [body mass index (BMI), age, disease duration, and disease stage] and ECG parameters [RR, PR, QRS, and QT intervals, and heart rate-corrected QT (QTc)] were analyzed. BMI was positively correlated with the PR and QRS intervals in patients with PD. The QRS interval was positively correlated with disease duration and Hoehn and Yahr stage, and the QT interval and QTc were positively correlated with age. Clinical features and ECG parameters are likely to be closely associated with each other. Several ECG parameters reflect autonomic dysfunction or disease progression. Clinicians should pay more attention to ECG parameters in the treatment of PD patients.
我们研究了帕金森病（PD）患者的临床特征与心电图（ECG）参数之间的关系。纳入了156例PD患者。分析了他们的临床特征[体重指数（BMI）、年龄、病程和疾病分期]以及ECG参数[RR、PR、QRS和QT间期，以及心率校正QT（QTc）]。PD患者的BMI与PR和QRS间期呈正相关。QRS间期与病程以及Hoehn和Yahr分期呈正相关，QT间期和QTc与年龄呈正相关。临床特征和ECG参数可能彼此密切相关。几个ECG参数反映自主神经功能障碍或疾病进展。临床医生在治疗PD患者时应更加关注ECG参数。
