Bomio Claudio, Kabeshov Mikhail A, Lit Arthur R, Lau Shing-Hing, Ehlert Janna, Battilocchio Claudio, Ley Steven V
Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB21EW , UK . Email:
Chem Sci. 2017 Sep 1;8(9):6071-6075. doi: 10.1039/c7sc02264f. Epub 2017 Jun 15.
By means of computational and experimental mechanistic studies the fundamental role of boroxines in the reaction between diazo compounds and boronic acids was elucidated. Consequently, a selective metal-free carbon-carbon homologation of aryl and vinyl boroxines using TMSCHN, giving access to TMS-pinacol boronic ester products, was developed.
通过计算和实验机理研究，阐明了硼恶嗪在重氮化合物与硼酸反应中的基本作用。因此，开发了一种使用TMSCHN对芳基和乙烯基硼恶嗪进行选择性无金属碳-碳同系化反应，从而得到TMS-频哪醇硼酸酯产物的方法。
