A multicomponent approach for the preparation of homoallylic alcohols.

Here we report the generation of transient allylic boronic species, by reacting TMSCHN and -vinyl boronic acids, followed by their subsequent trapping with aldehydes as electrophiles to yield homoallylic alcohols. This metal-free reaction was initially discovered by the use of a flow chemistry approach to generate a variety of homoallylic alcohols in a straightforward fashion and then transferred to a batch protocol.