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细菌性脑膜炎一种罕见但正在增多的病因。

A rare yet emerging cause of bacterial meningitis.

作者信息

Peralta Diego P, Chang Aymara Y, Ariza-Hutchinson Angie, Ho Catherine A

机构信息

Division of Infectious Diseases, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, TX, 79905, USA.

Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, TX, 79905, USA.

出版信息

IDCases. 2018 Jan 9;11:61-63. doi: 10.1016/j.idcr.2018.01.002. eCollection 2018.

DOI:10.1016/j.idcr.2018.01.002
PMID:29619322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5881440/
Abstract

is a member of the complex. Although it is usually associated with infections in patients with cystic fibrosis, chronic granulomatous disease, and immunosuppression, central nervous infections are not commonly reported. Moreover, management of these infections is difficult due to multiple mechanisms of bacterial resistance to antimicrobial agents. We report a 55-year-old-man who developed meningitis after two episodes of central line-associated bloodstream infections. The patient was successfully treated with intravenous trimethoprim/sulfamethoxazole. is an emerging cause of meningitis with limited antibacterial treatment options. However, trimethoprim/sulfamethoxazole remains an effective agent with excellent penetration into the central nervous system. To our knowledge, this is the first case reported of complex meningitis identified to the species level as

摘要

是复合体的成员。虽然它通常与囊性纤维化、慢性肉芽肿病和免疫抑制患者的感染有关,但中枢神经系统感染并不常见。此外,由于细菌对抗菌药物产生耐药性的多种机制,这些感染的治疗很困难。我们报告一名55岁男性,在发生两起与中心静脉导管相关的血流感染后发生了脑膜炎。该患者接受静脉注射甲氧苄啶/磺胺甲恶唑治疗成功。是脑膜炎的一个新兴病因,抗菌治疗选择有限。然而,甲氧苄啶/磺胺甲恶唑仍然是一种有效的药物,对中枢神经系统有极佳的穿透力。据我们所知,这是首例报告的复合体脑膜炎,已鉴定到物种水平为

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e6e/5881440/f6f3c70f6042/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e6e/5881440/f6f3c70f6042/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e6e/5881440/f6f3c70f6042/gr1.jpg

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