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成人阴囊并殖吸虫病:两例报告及文献复习

Scrotal Paragonimiasis in adults: Two case reports and review of literature.

作者信息

Liang Tiancai, Liang Guobiao, Du Yang, Wang Xin, Wang Yuanliang, Chen Anjian, Chen Zongping, Du Jiang, Li Hao, Yu Lang

机构信息

Urological Department, the Affiliated Hospital of Zunyi Medical College, Zunyi, China.

出版信息

Medicine (Baltimore). 2018 Apr;97(14):e0328. doi: 10.1097/MD.0000000000010328.

DOI:10.1097/MD.0000000000010328
PMID:29620658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5902294/
Abstract

RATIONALE

Paragonimiasis is a parasitic disease caused by Paragonimus in the lungs; it can be divided into intrapulmonary type and extrapulmonary type. Adult patients with scrotal paragnonimus are rarely seen clinically and not widely reported in the literature. Here, we report 2 cases of scrotal paragonimiasis in adults and their treatment process.

PATIENT CONCERNS

Two young males sought medical advice because of scrotal masses. Both patients had the previous history of eating uncooked river crabs and presented with palpable quasicircular nodules of about 1.5 × 1.0 cm in testicles, which were well-defined, resilient in tenderness. The bilateral inguinal lymph nodes were not enlarged.

DIAGNOSIS AND INTERVENTIONS

The 2 patients underwent scrotal mass resection; postoperative pathology examination confirmed scrotum paragonimiasis. Both the patients were administered praziquantel after operation.

OUTCOMES

They were followed up for 1 year and 4 years, respectively; both recovered well, free from recurrence. Scrotum color Doppler ultrasound examination found no obvious abnormality.

LESSONS

Adult patients with scrotum paragonimiasis are rarely seen clinically. Moreover, its clinical manifestations are not typical that leads to missed diagnosis and misdiagnosis. Diagnosis of the disease needs to combine with disease histories, manifestations, and relevant auxiliary examinations. But the diagnosis can be confirmed only by histopathological examination. The main method for treatment of scrotal paragonimiasis is antiparasitic treatment. However, health education is crucial to prevent this disease and relapse.

摘要

理论依据

肺吸虫病是由肺吸虫寄生于肺部引起的寄生虫病,可分为肺内型和肺外型。成年阴囊肺吸虫病患者临床罕见,文献报道不多。在此,我们报告2例成年阴囊肺吸虫病患者及其治疗过程。

患者情况

两名年轻男性因阴囊肿物就诊。两名患者均有食用生河蟹史,睾丸可触及约1.5×1.0cm的类圆形结节,边界清晰,触之有弹性,压痛明显。双侧腹股沟淋巴结未肿大。

诊断与干预

两名患者均接受了阴囊肿物切除术;术后病理检查确诊为阴囊肺吸虫病。术后均给予吡喹酮治疗。

结果

分别随访1年和4年;两人恢复良好,无复发。阴囊彩色多普勒超声检查未发现明显异常。

经验教训

成年阴囊肺吸虫病患者临床罕见。此外,其临床表现不典型,易导致漏诊和误诊。该病的诊断需要结合病史、临床表现及相关辅助检查,但只有通过组织病理学检查才能确诊。阴囊肺吸虫病的主要治疗方法是抗寄生虫治疗。然而,健康教育对于预防该病及复发至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be66/5902294/f5a0451b716f/medi-97-e0328-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be66/5902294/1424f6301fa4/medi-97-e0328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be66/5902294/f5a0451b716f/medi-97-e0328-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be66/5902294/1424f6301fa4/medi-97-e0328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be66/5902294/f5a0451b716f/medi-97-e0328-g002.jpg

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本文引用的文献

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Gene diversity and genetic variation in lung flukes (genus Paragonimus).肺吸虫(并殖吸虫属)的基因多样性和遗传变异
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Rare case of paragonimiasis with involvement of the parotid gland alone in a 5-year-old boy.一名5岁男孩仅累及腮腺的肺吸虫病罕见病例。
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North American paragonimiasis (Caused by Paragonimus kellicotti) in the context of global paragonimiasis.
全球并殖吸虫病背景下的北美并殖吸虫病(由北美并殖吸虫引起)
Clin Microbiol Rev. 2009 Jul;22(3):415-46. doi: 10.1128/CMR.00005-08.
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Morphological description and life cycle of Paragonimus sp. (Trematoda: Troglotrematidae): causal agent of human paragonimiasis in Colombia.并殖吸虫属(吸虫纲:隐孔吸虫科)的形态学描述及生活史:哥伦比亚人体并殖吸虫病的病原体
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Paragonimiasis and the genus Paragonimus.肺吸虫病与肺吸虫属
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Recent progress in studies of paragonimus and paragonimiasis control in China.中国并殖吸虫及并殖吸虫病防治研究的最新进展
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