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理解失忆症的经典进展与最新进展。

Classic and recent advances in understanding amnesia.

作者信息

Allen Richard J

机构信息

School of Psychology, University of Leeds, Leeds, UK.

出版信息

F1000Res. 2018 Mar 16;7:331. doi: 10.12688/f1000research.13737.1. eCollection 2018.

Abstract

Neurological amnesia has been and remains the focus of intense study, motivated by the drive to understand typical and atypical memory function and the underlying brain basis that is involved. There is now a consensus that amnesia associated with hippocampal (and, in many cases, broader medial temporal lobe) damage results in deficits in episodic memory, delayed recall, and recollective experience. However, debate continues regarding the patterns of preservation and impairment across a range of abilities, including semantic memory and learning, delayed recognition, working memory, and imagination. This brief review highlights some of the influential and recent advances in these debates and what they may tell us about the amnesic condition and hippocampal function.

摘要

神经失忆症一直是并仍然是深入研究的焦点,其研究动力源于理解典型和非典型记忆功能以及所涉及的潜在脑基础。目前已达成共识,与海马体(在许多情况下,还包括更广泛的内侧颞叶)损伤相关的失忆症会导致情景记忆、延迟回忆和回忆体验方面的缺陷。然而,对于包括语义记忆与学习、延迟识别、工作记忆和想象力在内的一系列能力的保留和损伤模式,仍存在争议。这篇简短的综述突出了这些争议中的一些有影响力的最新进展,以及它们可能告诉我们的关于失忆症状况和海马体功能的信息。

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