Piatkiewicz Trevor Jozef, Traulsen Janine Marie, Holm-Larsen Tove
Section for Social and Clinical Pharmacy, Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Pharma Evidence, Farum, Denmark.
Pharmacoecon Open. 2018 Jun;2(2):109-123. doi: 10.1007/s41669-017-0044-1.
Our objectives were to explore the changes in the level of interest in risk-sharing agreements (RSAs) in the EU during the last 15 years and the underlying reasons for these changes.
A systematic literature review was conducted using PubMed, Scopus, Web of Science, and Embase. Articles identified were divided into 'quantitative articles' used to establish the level of interest and 'qualitative articles' used to identify the underlying trends in RSAs.
The literature search retrieved 2144 scientific articles. Data were extracted from 238 articles. Of these, 100 contained quantitative data and 138 contained qualitative data. The pace of articles being published about RSAs grew significantly in 2015, which related to the increase in interest in and knowledge about RSAs. The underlying reasons for the fluctuations were condensed into four overall themes: (1) push for value-based pricing, (2) economic crisis and further push to contain costs, (3) criticism of RSAs in the real world, and (4) diversification of RSAs to fit the purpose.
The overall level of interest in RSAs in the EU has been increasing since 2000; therefore, articles reporting the number of RSAs implemented and case studies have been steadily growing as evidence is becoming more readily available. The number of qualitative articles reporting and discussing the underlying reasons for these changes in interest has largely fluctuated over the last 15 years. Despite these fluctuations, interest in RSAs remains high.
我们的目标是探讨过去15年欧盟对风险分担协议(RSA)的兴趣水平变化及其背后的原因。
使用PubMed、Scopus、Web of Science和Embase进行系统的文献综述。所识别的文章分为用于确定兴趣水平的“定量文章”和用于识别RSA潜在趋势的“定性文章”。
文献检索共获得2144篇科学文章。从238篇文章中提取了数据。其中,100篇包含定量数据,138篇包含定性数据。2015年,关于RSA的文章发表速度显著加快,这与对RSA的兴趣和了解增加有关。波动的潜在原因归纳为四个总体主题:(1)推动基于价值的定价;(2)经济危机及进一步控制成本的压力;(3)对现实世界中RSA的批评;(4)RSA的多样化以适应目的。
自2000年以来,欧盟对RSA的总体兴趣水平一直在上升;因此,随着证据越来越容易获得,报告实施的RSA数量的文章和案例研究稳步增加。在过去15年中,报告和讨论兴趣变化背后原因的定性文章数量波动很大。尽管存在这些波动,对RSA的兴趣仍然很高。