Department of Health Services Research, Graduate School of Medicine, Japan; Department of Respiratory Medicine, Graduate School of Medicine, Japan.
Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Parkinsonism Relat Disord. 2018 Sep;54:25-29. doi: 10.1016/j.parkreldis.2018.03.028. Epub 2018 Apr 3.
Pneumonia is one of the most frequent reasons for hospitalization in patients with Parkinson's disease. The present study aimed to evaluate the impact of Parkinsonism on the clinical courses of elderly patients hospitalized for pneumonia.
We conducted a retrospective cohort study of patients aged ≥60 years who were hospitalized for pneumonia, using data from a national inpatient database in Japan. We performed one-to-four matching for age and sex between patients with and without Parkinsonism. Multivariable regression analyses were carried out for in-hospital mortality, length of stay, and discharge to home.
Patients with Parkinsonism had significantly lower in-hospital mortality than those without Parkinsonism (odds ratio, 0.81; 95% confidence interval, 0.74-0.89). Length of stay was 8.1% longer in patients with Parkinsonism. Patients with Parkinsonism were less likely to be discharged to home (odds ratio, 0.62; 95% confidence interval, 0.58-0.67).
Parkinsonism was not an independent predictor of in-hospital mortality, but was related to prolonged length of stay and discharge other than to home in patients with pneumonia.
肺炎是帕金森病患者住院的最常见原因之一。本研究旨在评估帕金森病对因肺炎住院的老年患者临床病程的影响。
我们使用来自日本全国住院患者数据库的数据,对年龄≥60 岁因肺炎住院的患者进行了回顾性队列研究。我们在年龄和性别方面对帕金森病患者和非帕金森病患者进行了一对一至四对一匹配。对住院死亡率、住院时间和出院回家进行了多变量回归分析。
帕金森病患者的住院死亡率明显低于非帕金森病患者(比值比,0.81;95%置信区间,0.74-0.89)。帕金森病患者的住院时间延长了 8.1%。帕金森病患者出院回家的可能性较小(比值比,0.62;95%置信区间,0.58-0.67)。
帕金森病不是住院死亡率的独立预测因素,但与肺炎患者的住院时间延长和非出院回家有关。