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初次全膝关节置换术中长时间与短时间止血带的短期疗效:一项随机对照试验。

Short term outcomes of long duration versus short duration tourniquet in primary total knee arthroplasty: A randomized controlled trial.

作者信息

Vaishya Raju, Agarwal Amit Kumar, Vijay Vipul, Tiwari Manish Kumar

机构信息

Department of Orthopaedics & Joint Replacement Surgery, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi 110076, India.

出版信息

J Clin Orthop Trauma. 2018 Jan-Mar;9(1):46-50. doi: 10.1016/j.jcot.2017.11.016. Epub 2017 Dec 2.

Abstract

INTRODUCTION

A tourniquet is used during the total knee replacement surgery to improve the visibility, to reduce the blood loss and for better cementation. Indirectly it decreases the duration of surgery and enhances the recovery of the patient. Their use however is controversial due to some side effects associated with the use of tourniquet. They may increase the risk of deep vein thrombosis and pulmonary embolism by causing venous stasis, endothelial damage and increased platelet adhesion secondary to distal limb ischemia.

MATERIAL AND METHODS

We conducted a randomized controlled trial (RCT) to examine the benefits and risks associated with the use of long duration over short duration tourniquets during TKA. The study was a prospective randomised control trial with a total of 80 knees (40 knees in each group) included in the study. The knees selected for surgery were randomly allocated to one of the two groups: Group A - long duration tourniquet (LT-group) or Group B - short duration tourniquet (ST-group).

RESULT

The average operating time in Group A (43.53±3.11 minutes) was statistically less significant than that of Group B (51.7±2.56 minutes). Intra-operative blood loss in Group B, was significantly more than that of Group A. Post-operative blood loss in the drain was more in long duration tourniquet group. Total blood loss (intra-operative + post-operative) was more in short duration tourniquet group. Pain score (using VAS scale) was comparable in both the groups at the end of the second and sixth week. At sixth weeks there was no significant difference in the range of motion in both the groups. The KSS score was not significantly different in both the groups in post operative period at first, second, and six weeks. There were no events of thrombo-embolism and deep vein thrombosis in either groups. In 11 patients (27.5%) of long duration tourniquet group, swelling, and redness of knee was seen post operatively as compared to three patients (7.5%) of short duration tourniquet group.

CONCLUSION

The use of a short duration tourniquet during TKA gives better symptomatic pain relief in the early postoperative period as compared to long duration use of tourniquet. However, this is associated with increased blood loss, more operating time and not having a clear operative field. We suggest that a rational thinking and reconsidering the practice of routine use of long duration tourniquet in each and every case of TKA is required.

摘要

引言

在全膝关节置换手术中使用止血带是为了提高视野清晰度、减少失血并实现更好的骨水泥固定。间接地,它还能缩短手术时间并促进患者康复。然而,由于使用止血带存在一些副作用,其应用存在争议。止血带可能会导致静脉淤滞、内皮损伤以及继发于远端肢体缺血的血小板黏附增加,从而增加深静脉血栓形成和肺栓塞的风险。

材料与方法

我们进行了一项随机对照试验(RCT),以研究在全膝关节置换术中使用长时间止血带与短时间止血带的利弊。该研究是一项前瞻性随机对照试验,共纳入80个膝关节(每组40个膝关节)。入选手术的膝关节被随机分配到两组之一:A组 - 长时间止血带组(LT组)或B组 - 短时间止血带组(ST组)。

结果

A组的平均手术时间(43.53±3.11分钟)在统计学上显著短于B组(51.7±2.56分钟)。B组的术中失血量显著多于A组。长时间止血带组引流管的术后失血量更多。短时间止血带组的总失血量(术中 + 术后)更多。在第二周和第六周结束时,两组的疼痛评分(使用视觉模拟评分法)相当。在第六周时,两组的活动范围没有显著差异。在术后第一周、第二周和第六周,两组的膝关节协会评分(KSS)没有显著差异。两组均未发生血栓栓塞和深静脉血栓形成事件。与短时间止血带组的3名患者(7.5%)相比,长时间止血带组有11名患者(27.5%)术后出现膝关节肿胀和发红。

结论

与长时间使用止血带相比,在全膝关节置换术中使用短时间止血带在术后早期能更好地缓解症状性疼痛。然而,这与失血量增加、手术时间延长以及手术视野不清晰有关。我们建议,对于全膝关节置换术的每一个病例,都需要进行理性思考并重新审视常规使用长时间止血带的做法。

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