Farooq Imran, Ali Saqib, Al-Khalifa Khalifa Sulaiman, Alhooshani Khalid
Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Saudi Dent J. 2018 Apr;30(2):161-165. doi: 10.1016/j.sdentj.2018.01.001. Epub 2018 Jan 31.
The aim of this pilot study was to perform chemical analysis and investigate the total and soluble fluoride concentrations in various brands of children toothpastes.
Three samples of five different commercial brands of children toothpastes were collected and divided into five groups; group A - Biorepair Oral Care toothpaste containing no fluoride (control), group B - Signal Kids Strawberry toothpaste having 500 ppm fluoride, group C - Aquafresh Milk Teeth toothpaste having 500 ppm fluoride, group D - Aquafresh Little Teeth toothpaste having 500 ppm fluoride, and group E - Siwak F Junior having 400 ppm F. The total fluoride (TF) and total soluble fluoride (TSF) concentration of the toothpastes was determined using fluoride ion selective electrode. Data were analysed using Paired sample -test.
The measured TF values were inconsistent with that of the declared concentrations by the manufacturers. Mean TF found in the toothpastes ranged between 2.37 and 515.74 ppm whereas, the mean TSF ranged between 2.00 and 503.4 ppm. For two groups, TF was more than the declared TF whereas for the other three groups, it was less than the declared concentration. All the differences between the declared and observed TF concentration were statistically significant (p < .05) except for one group. All the toothpastes demonstrated mean TSF slightly lower than their respective observed mean TF concentrations.
The analysis of TF and TSF concentrations revealed variations from the labelled claims. Therefore, some of the toothpastes may have doubtful anti-caries effectiveness owing to deficiency of total and soluble fluoride.
本试点研究的目的是进行化学分析，并调查各种品牌儿童牙膏中的总氟和可溶性氟浓度。
收集了五个不同商业品牌儿童牙膏的三个样本，并分为五组；A组——不含氟的Biorepair口腔护理牙膏（对照组），B组——含500 ppm氟的Signal Kids草莓牙膏，C组——含500 ppm氟的Aquafresh乳牙牙膏，D组——含500 ppm氟的Aquafresh小牙齿牙膏，E组——含400 ppm氟的Siwak F Junior牙膏。使用氟离子选择电极测定牙膏中的总氟（TF）和总可溶性氟（TSF）浓度。数据采用配对样本t检验进行分析。
测得的TF值与制造商宣称的浓度不一致。牙膏中测得的平均TF在2.37至515.74 ppm之间，而平均TSF在2.00至503.4 ppm之间。两组的TF高于宣称的TF，而其他三组则低于宣称的浓度。除一组外，宣称的TF浓度与观察到的TF浓度之间的所有差异均具有统计学意义（p < 0.05）。所有牙膏的平均TSF均略低于其各自观察到的平均TF浓度。
对TF和TSF浓度的分析表明，其与标签声明存在差异。因此，由于总氟和可溶性氟不足，一些牙膏的防龋效果可能令人怀疑。
