Universidade Federal do Amazonas. Faculdade de Odontologia. Programa de Pós-Graduação em Odontologia. Manaus, AM, Brasil.
Universidade Estadual de Campinas. Faculdade de Odontologia de Piracicaba. Departamento de Biociências. Piracicaba, SP, Brasil.
Rev Saude Publica. 2022 Mar 21;56:9. doi: 10.11606/s1518-8787.2022056003636. eCollection 2022.
To determine the anticaries potential of toothpastes distributed by the primary health care public clinics (UBS) of Manaus, AM.
Ninety-nine tubes of toothpaste from four commercial brands were collected from October 7, 2019 to October 11, 2019 in 16 UBS. They were assigned a code by brand and source UBS. According to the information on the packaging, the four brands and their batches were formulated with sodium monofluorophosphate (Na2FPO3) and most (91%) had calcium carbonate (CaCO3) as an abrasive. We determined the concentrations of total fluoride (TF = TSF + InsF) and total soluble fluoride (TSF = F ions- or FPO32-), to certify whether they were in compliance with resolution ANVISA RDC No. 530 (maximum of 1,500 ppm TF) and whether they had anticaries potential (minimum of 1,000 ppm TSF). The analyses were performed with a ion- specific electrode.
The concentrations (ppm F) of TF [mean; standard deviation (SD); n] found in toothpaste brands A (1,502.3; SD = 45.6; n = 33), B (1,135.5; SD = 52.7; n = 48) and D (936.8; SD = 20.5; N = 8) were close to those stated on the package, 1,500, 1,100 and 1,000 ppm F, respectively. In toothpaste C, we found a mean of 274.1 ppm (SD = 219.7; n = 10) of TF, which diverges from the declared concentration of 1,500 ppm F. In addition, the five tubes of lot no. 11681118 of toothpaste C did not contain fluoride. Regarding TSF, with the exception of toothpaste D (937.9; SD = 40.29), the others had a lower concentration than their respective TF.
We found serious problems of quantity and quality of fluoride in toothpaste distributed by the SUS in Manaus, which shows the need for surveillance of these products and confirms the urgency of revising resolution RDC No. 530.
确定亚马孙州（AM）基层医疗保健公立诊所（UBS）分发的牙膏的抗龋潜力。
2019 年 10 月 7 日至 10 月 11 日，从 16 家 UBS 共收集了 99 管来自四个商业品牌的牙膏。根据品牌和来源 UBS，对其进行编号。根据包装上的信息，这四个品牌及其批次都用单氟磷酸钠（Na2FPO3）制成，其中大多数（91%）含有碳酸钙（CaCO3）作为研磨剂。我们确定了总氟化物（TF = TSF + InsF）和总可溶性氟化物（TSF = F 离子-或 FPO32-）的浓度，以证明它们是否符合 ANVISA RDC No. 530（最大 1500ppm TF）的规定，以及它们是否具有抗龋潜力（最低 1000ppm TSF）。分析使用离子特异性电极进行。
我们发现，品牌 A（1502.3ppm；SD = 45.6；n = 33）、B（1135.5ppm；SD = 52.7；n = 48）和 D（936.8ppm；SD = 20.5；N = 8）的 TF [平均值；标准差（SD）；n] 浓度接近包装上的规定值，分别为 1500、1100 和 1000ppm F。然而，在品牌 C 的牙膏中，我们发现平均 TF 浓度为 274.1ppm（SD = 219.7；n = 10），与宣称的 1500ppm F 浓度不符。此外，品牌 C 的 11681118 批的五管牙膏不含氟化物。至于 TSF，除了牙膏 D（937.9ppm；SD = 40.29）之外，其他牙膏的浓度均低于各自的 TF。
我们发现亚马孙州基层医疗保健公立诊所分发的牙膏在氟化物的数量和质量方面存在严重问题，这表明需要对这些产品进行监测，并证实修订 RDC No. 530 的紧迫性。
