Nagata Yoshika, Yoshioka Manabu, Uramoto Hidetaka, Tsurudome Yosuke, Yamada Sohsuke, Hanagiri Takeshi, Tanaka Fumihiro
Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
J Breast Cancer. 2018 Mar;21(1):96-101. doi: 10.4048/jbc.2018.21.1.96. Epub 2018 Mar 23.
Malignant melanoma rarely originates from the female nipple. Tumors that develop on the skin of the breast are often subject to a delayed diagnosis. Cytologic examination provides excellent diagnostic capabilities and is a safe procedure with a lower risk of local implantation, compared to needle or incisional biopsy. We herein report a patient who underwent surgical resection of a primary malignant melanoma of the nipple. An elastic soft nodule was observed on the left nipple, and no abnormal lesions were identified in the breast. Eventually, a malignant melanoma was diagnosed from the clinical and cytological evaluation findings. This bulky tumor was classified as a stage IIIC nodular melanoma, with a thickness of 12 mm. The patient received adjuvant chemotherapy and exhibits no evidence of recurrence 7 years after surgery.
恶性黑色素瘤很少起源于女性乳头。发生在乳房皮肤的肿瘤往往诊断延迟。与针吸活检或切开活检相比,细胞学检查具有出色的诊断能力,且是一种安全的操作,局部种植风险较低。我们在此报告一例接受乳头原发性恶性黑色素瘤手术切除的患者。在左侧乳头观察到一个弹性软结节,乳房未发现异常病变。最终,根据临床和细胞学评估结果诊断为恶性黑色素瘤。这个巨大肿瘤被分类为IIIC期结节性黑色素瘤,厚度为12毫米。患者接受了辅助化疗,术后7年无复发迹象。