Qureshi Maryam, Zelinski Erin, Carlson Linda E
1 University of Calgary, Calgary, AB, Canada.
3 Alberta Health Services-Cancer Care, Calgary, AB, Canada.
Integr Cancer Ther. 2018 Sep;17(3):844-853. doi: 10.1177/1534735418762496. Epub 2018 Apr 9.
Cancer survivors use complementary therapies (CTs) for a variety of reasons; however, with interest and use reportedly on the rise and a widening range of products and practices available, there is a need to establish trends in and drivers of interest. We aimed to determine (1) frequencies of use, level of interest, and barriers for 30 specific CTs and (2) whether physical symptoms, perceived stress (PS), or spiritual well-being were related to interest levels.
A total of 212 cancer outpatients were surveyed at the Tom Baker Cancer Centre in Calgary, Canada.
Overall, up to 75% of survivors already used some form of CTs since their diagnosis. The most highly used were the following: vitamins B12 and D, multivitamins, calcium, and breathing and relaxation exercises. Those who had not used CTs indicated highest interest in massage, vitamin B12, breathing and relaxation, mindfulness-based stress reduction, and antioxidants. The most frequently reported barriers for all CTs were not knowing enough about what a therapy was and not having enough evidence on whether it worked. High PS predicted higher interest for all CTs, but spirituality was not significantly related to any. Physical symptoms, anxiety, and depression were significant predictors of interest for some CTs.
These findings provide a blueprint for future clinical efficacy trials and highlight the need for clinical practice guidelines.
癌症幸存者使用补充疗法(CTs)的原因多种多样;然而,据报道,随着人们对补充疗法的兴趣和使用呈上升趋势,且可用的产品和疗法范围不断扩大,有必要确定兴趣的趋势和驱动因素。我们旨在确定:(1)30种特定补充疗法的使用频率、兴趣程度和障碍;(2)身体症状、感知压力(PS)或精神幸福感是否与兴趣水平相关。
在加拿大卡尔加里的汤姆·贝克癌症中心对212名癌症门诊患者进行了调查。
总体而言,高达75%的幸存者自确诊以来已经使用了某种形式的补充疗法。使用频率最高的是以下几种:维生素B12和D、多种维生素、钙以及呼吸和放松练习。未使用补充疗法的人表示对按摩、维生素B12、呼吸和放松、基于正念的减压以及抗氧化剂最感兴趣。所有补充疗法最常报告的障碍是对疗法了解不足以及缺乏关于其是否有效的足够证据。高感知压力预示着对所有补充疗法的更高兴趣,但精神性与任何补充疗法均无显著关联。身体症状、焦虑和抑郁是某些补充疗法兴趣的重要预测因素。
这些发现为未来的临床疗效试验提供了蓝图,并突出了临床实践指南的必要性。