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流体流动塑造生物形态。

Fluid flows shaping organism morphology.

机构信息

Max Planck Institute for Dynamics and Self-Organization, Am Fassberg 17, 37077 Göttingen, Germany

出版信息

Philos Trans R Soc Lond B Biol Sci. 2018 May 26;373(1747). doi: 10.1098/rstb.2017.0112.

DOI:10.1098/rstb.2017.0112
PMID:29632264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5904298/
Abstract

A dynamic self-organized morphology is the hallmark of network-shaped organisms like slime moulds and fungi. Organisms continuously reorganize their flexible, undifferentiated body plans to forage for food. Among these organisms the slime mould  has emerged as a model to investigate how an organism can self-organize their extensive networks and act as a coordinated whole. Cytoplasmic fluid flows flowing through the tubular networks have been identified as the key driver of morphological dynamics. Inquiring how fluid flows can shape living matter from small to large scales opens up many new avenues for research. This article is part of the theme issue 'Self-organization in cell biology'.

摘要

动态自组织形态是网络状生物(如黏菌和真菌)的标志。生物不断地重新组织它们灵活的、未分化的身体结构,以寻找食物。在这些生物中,黏菌已经成为一个研究生物体如何自我组织它们广泛的网络并作为一个协调整体的模型。已经确定细胞质液流流过管状网络是形态动力学的关键驱动因素。探究液流如何从小尺度到大尺度塑造生命物质为许多新的研究途径开辟了道路。本文是“细胞生物学中的自组织”主题专刊的一部分。

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Optimal occlusion uniformly partitions red blood cells fluxes within a microvascular network.最佳闭塞均匀地划分微血管网络内的红细胞通量。
PLoS Comput Biol. 2017 Dec 15;13(12):e1005892. doi: 10.1371/journal.pcbi.1005892. eCollection 2017 Dec.
3
How Active Mechanics and Regulatory Biochemistry Combine to Form Patterns in Development.主动力学和调节生物化学如何结合形成发育中的模式。
Annu Rev Biophys. 2017 May 22;46:337-356. doi: 10.1146/annurev-biophys-070816-033602.
4
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Pruning to Increase Taylor Dispersion in Physarum polycephalum Networks.通过修剪增加多头绒泡菌网络中的泰勒色散
Phys Rev Lett. 2016 Oct 21;117(17):178103. doi: 10.1103/PhysRevLett.117.178103. Epub 2016 Oct 20.
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Allometry in Physarum plasmodium during free locomotion: size versus shape, speed and rhythm.游动期间黏菌原质团的异速生长:大小与形状、速度和节律
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