Onesto V, Villani M, Coluccio M L, Majewska R, Alabastri A, Battista E, Schirato A, Calestani D, Coppedé N, Cesarelli M, Amato F, Di Fabrizio E, Gentile F
Department of Experimental and Clinical Medicine, University of Magna Graecia, 88100, Catanzaro, Italy.
IMEM-CNR, Parco Area delle Scienze 37/A, 43124, Parma, Italy.
Nanoscale Res Lett. 2018 Apr 10;13(1):94. doi: 10.1186/s11671-018-2507-4.
Diatom shells are a natural, theoretically unlimited material composed of silicon dioxide, with regular patterns of pores penetrating through their surface. For their characteristics, diatom shells show promise to be used as low cost, highly efficient drug carriers, sensor devices or other micro-devices. Here, we demonstrate diatom shells functionalized with gold nanoparticles for the harvesting and detection of biological analytes (bovine serum albumin-BSA) and chemical pollutants (mineral oil) in low abundance ranges, for applications in bioengineering, medicine, safety, and pollution monitoring.
硅藻壳是一种天然的、理论上储量无限的由二氧化硅组成的材料，其表面有规则的孔隙图案。由于其特性，硅藻壳有望用作低成本、高效的药物载体、传感器设备或其他微设备。在此，我们展示了用金纳米粒子功能化的硅藻壳，用于在低丰度范围内捕获和检测生物分析物（牛血清白蛋白-BSA）和化学污染物（矿物油），以应用于生物工程、医学、安全和污染监测。
