De Tommasi Edoardo, De Luca Anna Chiara
National Research Council, Institute of Applied Sciences and Intelligent Systems "Eduardo Caianiello", Unit of Naples, Via P. Castellino 111, I-80131, Naples, Italy.
National Research Council, Institute for Endocrinology and Experimental Oncology "Gaetano Salvatore", Unit of Naples, Via P. Castellino 111, I-80131, Naples, Italy.
Biomed Opt Express. 2022 Apr 27;13(5):3080-3101. doi: 10.1364/BOE.457483. eCollection 2022 May 1.
Several living organisms are able to synthesize complex nanostructures provided with peculiar physical and chemical properties by means of finely-tuned, genetically controlled biomineralization processes. Frustules, in particular, are micro- and nano-structured silica shells produced by ubiquitous diatom microalgae, whose optical properties have been recently exploited in photonics, solar energy harvesting, and biosensing. Metallization of diatom biosilica, both in the shape of intact frustules or diatomite particles, can trigger plasmonic effects that in turn can find application in high-sensitive detection platforms, allowing to obtain effective nanosensors at low cost and on a large scale. The aim of the present review article is to provide a wide, complete overview on the main metallization techniques applied to diatom biosilica and on the principal applications of diatom-based plasmonic devices mainly but not exclusively in the fields of biochemical sensing, diagnostics and therapeutics.
几种生物能够通过精细调控、基因控制的生物矿化过程合成具有特殊物理和化学性质的复杂纳米结构。特别是硅藻壳，它是由无处不在的硅藻微藻产生的微米和纳米结构的二氧化硅壳，其光学特性最近已被应用于光子学、太阳能收集和生物传感领域。完整硅藻壳或硅藻土颗粒形状的硅藻生物二氧化硅金属化可以引发等离子体效应，进而可应用于高灵敏度检测平台，从而能够以低成本大规模获得有效的纳米传感器。本综述文章的目的是全面、完整地概述应用于硅藻生物二氧化硅的主要金属化技术，以及基于硅藻的等离子体器件的主要应用，主要但不限于生物化学传感、诊断和治疗领域。
