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第二信使 cAMP 在控制丝状真菌形态和代谢产物产生方面是否发挥了更复杂的作用?

Does the second messenger cAMP have a more complex role in controlling filamentous fungal morphology and metabolite production?

机构信息

Swedish Centre for Resource Recovery, University of Borås, Borås, Sweden.

Mycorena AB, Stena Center 1 A, Gothenburg, Sweden.

出版信息

Microbiologyopen. 2018 Aug;7(4):e00627. doi: 10.1002/mbo3.627. Epub 2018 Apr 6.

Abstract

The effect of second messenger cAMP on the physiological aspects of fungal cells such as pigmentation has been reported previously. However, their actual role in the cellular biochemical cascade that eventually affects the fungal growth morphology, such as mycelial pellet formation, is unclear. This article intends to open up the detailed study on the possible correlative effect of cAMP on the morphological and physiological growth aspects of filamentous fungi, with special emphasis on the industrial metabolite production.

摘要

先前已有报道称,第二信使 cAMP 会对真菌细胞的生理方面产生影响,如色素沉着。然而,其在细胞生化级联反应中的实际作用,即最终影响真菌生长形态(如菌丝球形成)的作用尚不清楚。本文旨在深入研究 cAMP 对丝状真菌形态和生理生长方面的可能相关影响,特别强调其对工业代谢产物生产的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9163/6079171/3955b9ca50d2/MBO3-7-e00627-g001.jpg

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