a Postgraduate Program in Biotechnology - RENORBIO , Focal Point - Federal University of Piauí , Teresina , Brazil.
b Medicinal Plants Research Center,Health Sciences Center , Federal University of Piauí , Teresina , Brazil.
Expert Opin Ther Pat. 2018 May;28(5):399-413. doi: 10.1080/13543776.2018.1459570. Epub 2018 Apr 10.
Rosmarinus officinalis L. is an aromatic plant with a number of biological properties. Recently, has been studied regarding its therapeutic potential. The objective of this study was to perform a systematic review on R. officinalis essential oil for its pharmacological properties and biotechnological applications.
The databases were searched for articles (Science Direct, Pub Med and Web of Science) and patents (INPI, WIPO and EPO) with publications on R. officinalis and associations with essential oil (EO-Ro), cardiovascular system, hypertension and cyclodextrin. We selected 305 articles on EO-Ro in the most diverse subjects and six articles with of R. officinalis associated with hypertension. 59 patents were analyzed. The results demonstrate how extensive the studies are on the biological activities with the extract and EO-Ro. These have shown effects antibacterial, antifungal, anti-inflammatory, antitumor and other. The properties exhibited by EO-Ro reinforce the use of this plant as a phytotherapeutic agent.
Although there are several pharmacological properties, studies on the prevention or treatment of cardiovascular diseases with EO-Ro are scarce, especially to evaluate the antihypertensive activity of EO-Ro. It has also become clear that EO-Ro can be exploited in different commercial products as supplement, cosmetics and new formulations.
迷迭香是一种具有多种生物特性的芳香植物。最近，人们对其治疗潜力进行了研究。本研究旨在对迷迭香精油的药理学特性和生物技术应用进行系统评价。
在 Science Direct、Pub Med 和 Web of Science 等数据库中搜索了有关迷迭香及其与精油（EO-Ro）、心血管系统、高血压和环糊精关联的文章和专利（INPI、WIPO 和 EPO）。我们选择了 305 篇关于 EO-Ro 的文章，涵盖了最广泛的主题，以及 6 篇与高血压相关的迷迭香文章。分析了 59 项专利。结果表明，关于提取物和 EO-Ro 的生物活性的研究非常广泛。这些研究显示了其具有抗菌、抗真菌、抗炎、抗肿瘤等作用。EO-Ro 表现出的特性增强了将这种植物作为植物疗法药物的使用。
尽管有多种药理学特性，但关于 EO-Ro 预防或治疗心血管疾病的研究很少，特别是评估 EO-Ro 的降压活性的研究。此外，很明显 EO-Ro 可以在不同的商业产品中得到利用，例如补充剂、化妆品和新配方。
