From the Virginia Mason Medical Center, Seattle, Washington (D.B.A., N.A.H., R.S.J., S.C.Y.) the Washington Permanente Medical Group, Seattle, Washington (B.E.S.) Axio Research, Seattle, Washington (A.E.S.).
Anesthesiology. 2018 Jul;129(1):47-57. doi: 10.1097/ALN.0000000000002208.
The interscalene nerve block provides analgesia for shoulder surgery, but is associated with diaphragm paralysis. One solution may be performing brachial plexus blocks more distally. This noninferiority study evaluated analgesia for blocks at the supraclavicular and anterior suprascapular levels, comparing them individually to the interscalene approach.
One hundred-eighty-nine subjects undergoing arthroscopic shoulder surgery were recruited to this double-blind trial and randomized to interscalene, supraclavicular, or anterior suprascapular block using 15 ml, 0.5% ropivacaine. The primary outcome was numeric rating scale pain scores analyzed using noninferiority testing. The predefined noninferiority margin was one point on the 11-point pain scale. Secondary outcomes included opioid consumption and pulmonary assessments.
All subjects completed the study through the primary outcome analysis. Mean pain after surgery was: interscalene = 1.9 (95% CI, 1.3 to 2.5), supraclavicular = 2.3 (1.7 to 2.9), suprascapular = 2.0 (1.4 to 2.6). The primary outcome, mean pain score difference of supraclavicular-interscalene was 0.4 (-0.4 to 1.2; P = 0.088 for noninferiority) and of suprascapular-interscalene was 0.1 (-0.7 to 0.9; P = 0.012 for noninferiority). Secondary outcomes showed similar opioid consumption with better preservation of vital capacity in the anterior suprascapular group (90% baseline [P < 0.001]) and the supraclavicular group (76% [P = 0.002]) when compared to the interscalene group (67%).
The anterior suprascapular block, but not the supraclavicular, provides noninferior analgesia compared to the interscalene approach for major arthroscopic shoulder surgery. Pulmonary function is best preserved with the anterior suprascapular nerve block.
经斜角肌间神经阻滞可提供肩部手术的镇痛,但与膈神经麻痹有关。一种解决方案可能是更远处行臂丛神经阻滞。本非劣效性研究评估了锁骨上和前肩胛上水平阻滞的镇痛效果,分别将其与经斜角肌间入路进行比较。
本双盲试验纳入了 189 名接受关节镜肩关节手术的患者,将其随机分为经斜角肌间、锁骨上或前肩胛上阻滞组,每组使用 15ml0.5%罗哌卡因。主要结局是采用非劣效性检验分析数字评分量表疼痛评分。预设的非劣效性边界为 11 分疼痛量表上的 1 分。次要结局包括阿片类药物消耗和肺部评估。
所有患者均完成了主要结局分析。术后平均疼痛:经斜角肌间=1.9(95%CI,1.3 至 2.5),锁骨上=2.3(1.7 至 2.9),肩胛上=2.0(1.4 至 2.6)。主要结局,锁骨上-经斜角肌间的平均疼痛评分差值为 0.4(-0.4 至 1.2;P=0.088 时非劣效性),肩胛上-经斜角肌间的平均疼痛评分差值为 0.1(-0.7 至 0.9;P=0.012 时非劣效性)。次要结局显示,与经斜角肌间组相比,前肩胛上组(90%基础值,P<0.001)和锁骨上组(76%,P=0.002)的阿片类药物消耗相似,肺活量保存更好。
与经斜角肌间入路相比,前肩胛上神经阻滞(而非锁骨上阻滞)为主要关节镜肩关节手术提供了非劣效的镇痛效果。前肩胛上神经阻滞可更好地保护肺功能。