• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

盘状红斑狼疮患者出现类似慢性睑缘炎的表现——病例系列

Chronic blepharitis like picture in patients with Discoid lupus erythematosis - Case series.

作者信息

Jisha K, Rajesh P S, Kurien George, Sathish Gargi, Vijayamma N

出版信息

Nepal J Ophthalmol. 2017 Jul;9(18):175-179. doi: 10.3126/nepjoph.v9i2.19264.

DOI:10.3126/nepjoph.v9i2.19264
PMID:29634708
Abstract

BACKGROUND

Blepharitis is a very common condition encountered in ophthalmology outpatient care department. Dermatological diseases like seborrheic keratopathy and rosacea have been frequently discussed as being associated with blepharitis. However Discoid lupus erythematosis [DLE], an autoimmune condition has only rarely been reported to involve the eyelids mimicking blepharitis. DLE affecting the eyelids can produce significant morbidity with lid deformities, trichiasis and symblepharon if left untreated.

OBJECTIVE

To report three consecutive cases of DLE with eyelid lesions mimicking blepharitis. They presented to the department of ophthalmology at our institute from April 2014 to March 2016. The first case presented with involvement of lower eyelid in one eye. She was having multiple skin lesions which on biopsy confirmed the diagnosis of DLE. The second case was a diagnosed case of DLE who received treatment 4 years back and came with relapse of the disease affecting the eyelid. The third case was a recently biopsy confirmed case of DLE with multiple skin lesions along with bilateral eyelid involvement. Two of them had madarosis and one case had destruction of the outer lid margin at presentation. All three cases responded well to treatment with Hydrxychloroquin.

CONCLUSION

The discoid lesions of DLE affecting the eyelids can mimic the appearance of chronic blepharitis. Ophthalmologists should be aware that DLE is a possibility while dealing with an atypical case of chronic blepharitis. Early diagnosis and treatment can prevent deformities of eyelid.

摘要

背景

睑缘炎是眼科门诊常见的病症。脂溢性角化病和酒渣鼻等皮肤病常被讨论与睑缘炎有关。然而,盘状红斑狼疮(DLE)这种自身免疫性疾病仅有极少报道累及眼睑,表现类似睑缘炎。如果不治疗,累及眼睑的DLE可导致严重的并发症,如眼睑畸形、倒睫和睑球粘连。

目的

报告3例连续的表现类似睑缘炎的眼睑病变的DLE病例。这些病例于2014年4月至2016年3月就诊于我院眼科。第一例为单眼下睑受累。她有多处皮肤病变,活检确诊为DLE。第二例是4年前确诊的DLE病例,此次因疾病复发累及眼睑前来就诊。第三例是最近经活检确诊的DLE病例,有多处皮肤病变且双侧眼睑受累。其中2例有睫毛脱落,1例就诊时外睑缘破坏。所有3例对羟氯喹治疗反应良好。

结论

累及眼睑的DLE盘状病变可类似慢性睑缘炎的表现。眼科医生在处理非典型慢性睑缘炎病例时应意识到存在DLE的可能性。早期诊断和治疗可预防眼睑畸形。

相似文献

1
Chronic blepharitis like picture in patients with Discoid lupus erythematosis - Case series.盘状红斑狼疮患者出现类似慢性睑缘炎的表现——病例系列
Nepal J Ophthalmol. 2017 Jul;9(18):175-179. doi: 10.3126/nepjoph.v9i2.19264.
2
Discoid lupus erythematosus of the eyelids associated with staphylococcal blepharitis and Meibomian gland dysfunction.眼睑盘状红斑狼疮伴葡萄球菌性睑缘炎和睑板腺功能障碍。
Clin Exp Dermatol. 2006 Jan;31(1):77-9. doi: 10.1111/j.1365-2230.2005.01988.x.
3
Palpebral involvement as a presenting and sole manifestation of discoid lupus erythematosus.睑部受累作为盘状红斑狼疮的首发及唯一表现
ScientificWorldJournal. 2010 Nov 4;10:2130-1. doi: 10.1100/tsw.2010.209.
4
Severe chronic blepharitis and scarring ectropion associated with discoid lupus erythematosus.严重慢性睑缘炎及瘢痕性睑外翻与盘状红斑狼疮相关。
Clin Exp Optom. 2013 Jan;96(1):124-5. doi: 10.1111/j.1444-0938.2012.00777.x. Epub 2012 Jul 30.
5
Discoid lupus erythematosus masquerading as chronic blepharoconjunctivitis.伪装成慢性睑结膜炎的盘状红斑狼疮。
Ophthalmology. 2005 May;112(5):e19-23. doi: 10.1016/j.ophtha.2005.01.035.
6
[Discoid lupus erythematosus with eyelid involvement. A series of nine patients].[累及眼睑的盘状红斑狼疮。9例患者系列报道]
J Fr Ophtalmol. 2007 Mar;30(3):247-9. doi: 10.1016/s0181-5512(07)89585-4.
7
Discoid lupus erythematosus presenting as asymmetric posterior blepharitis.表现为不对称性后部睑缘炎的盘状红斑狼疮。
Am J Ophthalmol. 1997 Nov;124(5):707-9. doi: 10.1016/s0002-9394(14)70920-1.
8
Discoid lupus erythematosus of the eyelids.眼睑盘状红斑狼疮
Ophthalmology. 1983 Dec;90(12):1389-98. doi: 10.1016/s0161-6420(83)34367-0.
9
Discoid lupus erythematosus presenting as madarosis.盘状红斑狼疮表现为睫毛脱落。
Am J Ophthalmol. 2003 Sep;136(3):545-6. doi: 10.1016/s0002-9394(03)00231-9.
10
[Discoid lupus erythematosus involving the eyelids: 4 cases].[累及眼睑的盘状红斑狼疮:4例]
Ann Dermatol Venereol. 2004 Jan;131(1 Pt 1):58-60. doi: 10.1016/s0151-9638(04)93544-2.

引用本文的文献

1
A Rare Manifestation of Discoid Lupus Erythematosus Solely in the Lower Eyelid of a Young Man.仅累及青年男性下眼睑的盘状红斑狼疮罕见表现。
Cureus. 2023 Oct 13;15(10):e47002. doi: 10.7759/cureus.47002. eCollection 2023 Oct.
2
Treatment of Discoid Lupus Erythematosus with Upadacitinib: A Case Report.乌帕替尼治疗盘状红斑狼疮:一例报告
Clin Cosmet Investig Dermatol. 2023 Oct 9;16:2793-2800. doi: 10.2147/CCID.S419344. eCollection 2023.