Kopsachilis Nikolaos, Tsaousis Konstantinos T, Tourtas Theofilos, Tsinopoulos Ioannis T
2nd Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Clin Exp Optom. 2013 Jan;96(1):124-5. doi: 10.1111/j.1444-0938.2012.00777.x. Epub 2012 Jul 30.
Discoid lupus erythematosus is a common form of chronic cutaneous lupus erythematosus, an autoimmune inflammatory disease that affects most of the human organs, including the skin, kidneys, joints, heart and lungs. We describe a 45-year-old Caucasian woman with a 21-year history of eyelid redness and irritation. She had been treated with antibiotics, steroids and eyelid hygiene, a therapy that resulted to brief periods of relief of symptoms. In the last 12 months, her symptoms seemed to have exacerbated, despite the administration of a local therapy. Following biopsy, a diagnosis of discoid lupus erythematosus was confirmed and the patient was placed on a systemic therapy with hydroxychloroquine. The eyelid inflammation decreased but severe scarring of the marginal eyelids persisted, resulting in cicatricial ectropion.
盘状红斑狼疮是慢性皮肤型红斑狼疮的一种常见形式，慢性皮肤型红斑狼疮是一种自身免疫性炎症性疾病，会影响人体的大多数器官，包括皮肤、肾脏、关节、心脏和肺部。我们描述了一位45岁的白种女性，有21年的眼睑发红和刺激病史。她曾接受过抗生素、类固醇和眼睑清洁治疗，这种治疗使症状得到了短暂缓解。在过去12个月里，尽管进行了局部治疗，她的症状似乎仍在加重。活检后，盘状红斑狼疮的诊断得到证实，患者开始接受羟氯喹的全身治疗。眼睑炎症减轻，但睑缘严重瘢痕形成持续存在，导致瘢痕性睑外翻。
