Department of Neurology, Pomeranian Medical University, Szczecin, Poland.
Institute of Psychology, University of Szczecin, Szczecin, Poland.
PLoS One. 2018 Apr 10;13(4):e0194117. doi: 10.1371/journal.pone.0194117. eCollection 2018.
Multiple Sclerosis (MS) is the most common, primary neurogenic cause of disability among young adults. We investigated demographic and clinical factors associated with unemployment on the example of 150 MS patients receiving immunomodulatory treatment in Poland. This study was based on clinical evaluation and collection of self-reported questionnaires, with an attention to self-motivation, severe fatigue and moderate disability. Patients who were unemployed (40% of all patients) had a mean disease duration of almost 5 years. Older (p<0.001), less educated (p = 0.007) and more severely disabled patients (p<0,001) were most likely to be unemployed. Moderate disability (OR = 11.089 95% CI: 4.11-34.201, p<0,001), severe fatigue (OR = 2.625 95% CI: 1.02-6.901, p = 0,046) and lower level of self-motivation (KNS) (OR = 0.947, 95% CI: 0.896-0.006, p = 0.042) were independently associated with unemployment.
多发性硬化症（MS）是年轻成年人中最常见的原发性神经源性致残原因。我们以在波兰接受免疫调节治疗的 150 名 MS 患者为例，研究了与失业相关的人口统计学和临床因素。这项研究基于临床评估和自我报告问卷的收集，重点关注自我激励、严重疲劳和中度残疾。失业的患者（占所有患者的 40%）的平均疾病持续时间近 5 年。年龄较大（p<0.001）、受教育程度较低（p=0.007）和残疾程度较重的患者（p<0.001）最有可能失业。中度残疾（OR=11.089 95%CI:4.11-34.201，p<0.001）、严重疲劳（OR=2.625 95%CI:1.02-6.901，p=0.046）和较低的自我激励水平（KNS）（OR=0.947，95%CI:0.896-0.006，p=0.042）与失业独立相关。
