Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, South Korea.
Department of Biostatistics, The Catholic University of Korea College of Medicine, Seoul, Korea.
PLoS One. 2018 Apr 10;13(4):e0195713. doi: 10.1371/journal.pone.0195713. eCollection 2018.
As persons with stroke are surviving longer, monitoring and managing their quality of life is becoming important. We reviewed the Korea National Health and Nutrition Examination Survey (KNHANES) in order to evaluate the health-related quality of life (HRQoL) in stroke survivors as measured by the Euro Quality of Life-5D (EQ-5D), and to find out influencing factors. A total of 42,500 subjects were enrolled in the KNHANES, and 575 of them were persons with stroke. The EQ-5D index was lower in persons with stroke than those without stroke, when adjusted for age and sex (with stroke: 0.757±0.012, without stroke: 0.948±0.001, p < .0001). Dimension-specific influencing factors of HRQoL were observed in persons with stroke; mobility problems increased with old age; self-care problems increased with old age and depression; usual activity problems increased with old age, low income, absence of economic activity, and depression; pain/discomfort problems increased with low income. The EQ-5D index was lower in stroke survivors with older age, hypertension, diabetes mellitus, and lack of regular exercise. This is the first study to utilize nationally representative data of the Korean population to investigate the effect of stroke on HRQoL and explore the dimension-specific influencing factors. Further development of rehabilitative interventions for post-stroke depression, vocational rehabilitation, and tailored programs for encouraging physical activity may be needed to improve the HRQoL in Korean stroke survivors.
随着中风患者存活时间的延长，监测和管理他们的生活质量变得越来越重要。我们回顾了韩国国家健康和营养检查调查（KNHANES），以评估中风幸存者的健康相关生活质量（HRQoL），并找出影响因素。共有 42500 名受试者参加了 KNHANES，其中 575 名是中风患者。在调整年龄和性别后，中风患者的 EQ-5D 指数低于无中风患者（中风：0.757±0.012，无中风：0.948±0.001，p<0.0001）。在中风患者中观察到了 HRQoL 的特定维度影响因素；行动不便问题随着年龄的增长而增加；自理问题随着年龄的增长和抑郁而增加；日常活动问题随着年龄的增长、低收入、无经济活动和抑郁而增加；疼痛/不适问题随着收入的减少而增加。年龄较大、患有高血压、糖尿病和缺乏规律运动的中风幸存者的 EQ-5D 指数较低。这是第一项利用韩国人口代表性数据调查中风对 HRQoL 的影响并探索特定维度影响因素的研究。可能需要进一步开发针对中风后抑郁、职业康复和鼓励身体活动的定制计划的康复干预措施，以提高韩国中风幸存者的 HRQoL。
