1 Department of Biomechanics, Medicine and Locomotor Apparatus Rehabilitation - Ribeirão Preto Medical School, , Ribeirão Preto, Sao Paulo, Brazil.
2 Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, , Ribeirão Preto, Sao Paulo, Brazil.
Cephalalgia. 2019 Jan;39(1):29-37. doi: 10.1177/0333102418769948. Epub 2018 Apr 10.
To assess the presence and handicap due to vestibular symptoms in three subgroups of patients with migraine and controls.
Women between 18-55 years old were diagnosed by headache specialists and stratified as migraine with aura (n = 60), migraine without aura (n = 60), chronic migraine (n = 60) and controls (n = 60). Information regarding demographics, headache and vestibular symptoms were collected in this cross-sectional study. The self-perceived handicap related to vestibular symptoms was assessed through the Dizziness Handicap Inventory questionnaire.
A total of 85% of women with migraine with aura and chronic migraine had vestibular symptoms contrasted to 70% of the migraine without aura group ( p < 0.05), and 12% of the control group reported symptoms ( p < 0.0001). Patients with migraine exhibited greater Dizziness Handicap Inventory scores than controls ( p < 0.001); and migraine with aura and chronic migraine groups reached greater scores than migraine without aura ( p < 0.01). Presence of migraine is associated with a greater risk of vestibular symptoms (migraine without aura: 5.20, migraine with aura: 6.60, chronic migraine:6.20, p < 0.0003) and with a greater risk of moderate-to-severe handicap (migraine without aura: 20.0, migraine with aura: 40.0, chronic migraine: 40.0, p < 0.0003). The presence of aura and greater migraine frequency adds to the risk of any handicap (migraine with aura: 1.9, chronic migraine: 1.7, p < 0.04) and to the risk of moderate-to-severe handicap (migraine with aura: 2.0, chronic migraine: 2.0, p < 0.0003). Migraine aura, intensity and frequency predict 36% of the dizziness handicap.
The prevalence of vestibular symptoms is increased in migraine during and between headache attacks, particularly in migraine with aura and chronic migraine along with an increased handicap due to those symptoms. Vestibular symptoms among subgroups of migraine should be considered when evaluating the functional impact of migraine.
评估偏头痛患者和对照组中三组患者前庭症状的存在及其残疾程度。
本横断面研究纳入了 18-55 岁的女性偏头痛患者，由头痛专家进行诊断，并分为偏头痛伴先兆（n=60）、偏头痛不伴先兆（n=60）、慢性偏头痛（n=60）和对照组（n=60）。该研究收集了有关人口统计学、头痛和前庭症状的信息。通过头晕残障量表评估与前庭症状相关的自我感知残疾程度。
与偏头痛不伴先兆组（70%）相比，偏头痛伴先兆和慢性偏头痛组的女性中分别有 85%（p<0.05）和 70%（p<0.05）出现前庭症状，对照组中报告有症状的女性为 12%（p<0.0001）。偏头痛患者的头晕残障量表评分高于对照组（p<0.001）；偏头痛伴先兆和慢性偏头痛组的评分高于偏头痛不伴先兆组（p<0.01）。偏头痛的存在与前庭症状的风险增加相关（偏头痛不伴先兆：5.20；偏头痛伴先兆：6.60；慢性偏头痛：6.20；p<0.0003），与中重度残疾的风险增加相关（偏头痛不伴先兆：20.0；偏头痛伴先兆：40.0；慢性偏头痛：40.0；p<0.0003）。先兆的存在和更高的偏头痛频率增加了任何残疾的风险（偏头痛伴先兆：1.9；慢性偏头痛：1.7；p<0.04），以及中重度残疾的风险（偏头痛伴先兆：2.0；慢性偏头痛：2.0；p<0.0003）。偏头痛的先兆、强度和频率可预测 36%的头晕残疾程度。
偏头痛发作期间和发作之间，前庭症状的发生率在偏头痛患者中增加，尤其是偏头痛伴先兆和慢性偏头痛患者，这些症状导致残疾程度增加。在评估偏头痛的功能影响时，应考虑偏头痛亚组中的前庭症状。
