Rizzo Renata, Pellico Alessandra, Silvestri Paola Rosaria, Chiarotti Flavia, Cardona Francesco
Università degli Studi di Catania, Catania, Italy.
Sapienza Università di Roma, Rome, Italy.
Front Psychiatry. 2018 Mar 27;9:100. doi: 10.3389/fpsyt.2018.00100. eCollection 2018.
The existing literature on the treatment of pediatric chronic tic disorder (CTD) and Tourette syndrome (TS) indicates that both behavioral therapy (BT) and pharmacotherapy (PT) are effective for reducing symptoms.
To evaluate the efficacy of BT compared to psychoeducation (PE) or PT for reducing tics and co-occurring symptoms and for improving quality of life (QoL) in a sample of youths with CTD and TS.
A 10 weeks, 2 sites (Catania, Rome) randomized controlled trial. Participants were randomized to receive one of the following treatments: BT, PE, or PT.
110 outpatients aged between 8 and 17 years affected by CTD or TS.
Patients in the BT and PT groups showed a significant reduction in the severity of tic symptoms, while the PE group did not show any improvement. PT was more effective for reducing obsessive compulsive symptoms than BT, while PE group did not show any improvement. Both BT and PT groups showed an improvement in most QoL domains, whereas no differences were found in the PE group.
BT is as effective as pharmacological therapy in the treatment of tic disorders in children and adolescents, thus offering an alternative to medications for CTD and TS.
现有关于儿童慢性抽动障碍（CTD）和妥瑞氏症（TS）治疗的文献表明，行为疗法（BT）和药物疗法（PT）在减轻症状方面均有效。
在患有CTD和TS的青少年样本中，评估BT与心理教育（PE）或PT相比，在减轻抽动症状和共病症状以及改善生活质量（QoL）方面的疗效。
一项为期10周、在2个地点（卡塔尼亚、罗马）进行的随机对照试验。参与者被随机分配接受以下治疗之一：BT、PE或PT。
110名年龄在8至17岁之间受CTD或TS影响的门诊患者。
BT组和PT组患者的抽动症状严重程度显著降低，而PE组未显示任何改善。PT在减轻强迫症状方面比BT更有效，而PE组未显示任何改善。BT组和PT组在大多数生活质量领域均有改善，而PE组未发现差异。
BT在治疗儿童和青少年抽动障碍方面与药物治疗同样有效，从而为CTD和TS的治疗提供了药物之外的另一种选择。
