伴有i(7q)和t(9;9)(p22;p24)的B细胞系急性淋巴细胞白血病
B-cell lineage acute lymphoblastic leukemia with i(7q) and t(9;9)(p22;p24).
作者信息
Takeda T, Takagi A, Zaike Y, Hirai M, Kawakami M, Mori M, Ohyashiki K, Ikeuchi T
机构信息
Department of Laboratory Medicine and Hematology Section, Tokyo Metropolitan Geriatric Hospital, Japan.
出版信息
Cancer Genet Cytogenet. 1988 Feb;30(2):295-9. doi: 10.1016/0165-4608(88)90198-7.
A 61-year-old Japanese male with acute lymphoblastic leukemia (ALL) is reported. Surface marker examinations revealed that the leukemic cells were of a B-cell lineage; the cells had common ALL antigens, Ia-like antigens, and B1 and B4 antigens. Chromosome analysis showed abnormalities of t(9;9)(p22;p24), as well as an isochromosome for the long arm of chromosome 7. The heritable fragile site at 9p was not detected in the peripheral blood cells of this patient at remission phase.
报告了一名61岁患急性淋巴细胞白血病（ALL）的日本男性。表面标志物检查显示白血病细胞为B细胞系；这些细胞具有常见的ALL抗原、Ia样抗原以及B1和B4抗原。染色体分析显示存在t(9;9)(p22;p24)异常，以及7号染色体长臂的等臂染色体。在该患者缓解期的外周血细胞中未检测到9p处的遗传性脆性位点。
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