Mann Ian, Sandler Belinda, Linton Nick, Kanagaratnam Prapa
Imperial College Healthcare NHS TrustLondon, UK.
Arrhythm Electrophysiol Rev. 2018 Mar;7(1):49-54. doi: 10.15420/aer.2017.40.3.
Understanding the mechanisms responsible for driving AF is key to improving the procedural success for AF ablation. In this review, we look at some of the proposed drivers of AF, the disagreement between experts and the challenges confronted in attempting to map AF. Defining a 'driver' is also controversial, but for the purposes of this review we will consider an AF driver to be either a focal or localised source demonstrating fast, repetitive activity that propagates outward from this source, breaking down in to disorganisation further away from its origin.
了解导致房颤的机制是提高房颤消融手术成功率的关键。在本综述中,我们探讨了一些提出的房颤驱动因素、专家之间的分歧以及试图绘制房颤图谱时面临的挑战。定义一个“驱动因素”也存在争议,但出于本综述的目的,我们将房颤驱动因素视为一个局灶性或局部性的源头,其表现出快速、重复性活动,并从该源头向外传播,在远离其起源处演变为紊乱状态。