Gillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Department of Paediatric Speech and Language Pathology, Queen Silvia Children's Hospital, Gothenburg, Sweden.
Acta Paediatr. 2018 Oct;107(10):1739-1749. doi: 10.1111/apa.14358. Epub 2018 Apr 26.
This study identified whether children who had screened positive for either developmental language disorder (DLD) or autism spectrum disorder (ASD) at the age of 2.5 years had neurodevelopmental assessments five years later.
Our study cohort were 288 children born from 1 July 2008 to 20 June 2009 who screened positive for DLD and, or, ASD at 2.5 years. Of these, 237 children were referred to, and assessed, at the Paediatric Speech and Language Pathology clinic (n = 176) or the Child Neuropsychiatry Clinic (n = 61) at the Queen Silvia Children's Hospital, Gothenburg, Sweden. Clinical registers covering all relevant outpatient clinics were reviewed five years later with regard to established diagnoses.
When the 237 were followed up five years later, 96 (40%) had established neurodevelopmental disorders or problems, often beyond DLD and ASD. Co-existing problems were common in this cohort and multidisciplinary assessments were indicated. The other 60% did not appear in subsequent clinic records. It is likely that this 40% was a minimum rate and that more children will be referred for developmental problems later.
Five years after they had been screened positive for DLD and, or autism at 2.5 years, 40% of our cohort had remaining or other developmental problems.
本研究旨在确定在 2.5 岁时被诊断为发育性语言障碍(DLD)或自闭症谱系障碍(ASD)的儿童,在五年后是否进行了神经发育评估。
我们的研究对象是 2008 年 7 月 1 日至 2009 年 6 月 20 日期间出生的 288 名儿童,他们在 2.5 岁时被筛查出患有 DLD 和/或 ASD。其中,237 名儿童被转介到瑞典哥德堡皇后西尔维亚儿童医院的儿童言语语言病理学诊所(n=176)或儿童神经精神病学诊所(n=61)进行评估。五年后,通过审查涵盖所有相关门诊诊所的临床记录,了解已建立的诊断。
当这 237 名儿童被随访五年后,有 96 名(40%)患有明确的神经发育障碍或问题,这些问题通常不仅限于 DLD 和 ASD。该队列中常见共患问题,需要进行多学科评估。另外 60%的儿童在后续的诊所记录中未出现问题。这 40%可能是一个最低的比率,而且可能会有更多的儿童以后会因发育问题而被转介。
在他们 2.5 岁时被筛查出患有 DLD 和/或自闭症五年后,我们队列的 40%仍存在或有其他发育问题。