National Centers for Disease Control and Public Health, Tbilisi, Georgia.
University of Michigan, Ann Arbor, Michigan.
Am J Trop Med Hyg. 2018 Jun;98(6):1870-1875. doi: 10.4269/ajtmh.17-0874. Epub 2018 Apr 5.
Infections caused by viruses of the parapoxvirus (PPV) genus, including orf and pseudocowpox viruses, are frequently seen in both humans and animals in many regions of the world. These infections are often misdiagnosed or neglected because of the lack of clinician awareness, inadequate diagnostic capacity, and their relatively mild disease presentation, which may result in affected individuals not seeking medical attention. Although PPV infections should be routinely considered in patients with cutaneous lesions, especially in those who have occupational exposure to farm animals, they are often excluded from the differential diagnosis because they are not perceived as serious, resulting in underestimation of the burden of disease. Since 2014, significant enhancements to Georgia's epidemiologic and laboratory capacity have made PPV surveillance and detection possible. In this study, we present information on 27 confirmed cases of PPV infection reported to Georgia's national surveillance system from January 2016 through January 2017.
在世界许多地区,副痘病毒(PPV)属的病毒引起的感染,包括羊口疮病毒和假性牛痘病毒,在人和动物中都很常见。由于临床医生认识不足、诊断能力不足以及疾病表现相对较轻,这些感染经常被误诊或忽视,这可能导致受影响的个体不去寻求医疗。虽然在患有皮肤损伤的患者中应常规考虑 PPV 感染,特别是那些有职业接触农场动物的患者,但由于它们不被视为严重疾病,因此常常被排除在鉴别诊断之外,从而低估了疾病负担。自 2014 年以来,格鲁吉亚在流行病学和实验室能力方面取得了重大进展,使 PPV 的监测和检测成为可能。在本研究中,我们介绍了 2016 年 1 月至 2017 年 1 月格鲁吉亚国家监测系统报告的 27 例确诊的 PPV 感染病例的信息。