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佐治亚国的副痘病毒感染:病例系列。

Parapoxvirus Infections in the Country of Georgia: A Case Series.

机构信息

National Centers for Disease Control and Public Health, Tbilisi, Georgia.

University of Michigan, Ann Arbor, Michigan.

出版信息

Am J Trop Med Hyg. 2018 Jun;98(6):1870-1875. doi: 10.4269/ajtmh.17-0874. Epub 2018 Apr 5.

DOI:10.4269/ajtmh.17-0874
PMID:29637879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6086165/
Abstract

Infections caused by viruses of the parapoxvirus (PPV) genus, including orf and pseudocowpox viruses, are frequently seen in both humans and animals in many regions of the world. These infections are often misdiagnosed or neglected because of the lack of clinician awareness, inadequate diagnostic capacity, and their relatively mild disease presentation, which may result in affected individuals not seeking medical attention. Although PPV infections should be routinely considered in patients with cutaneous lesions, especially in those who have occupational exposure to farm animals, they are often excluded from the differential diagnosis because they are not perceived as serious, resulting in underestimation of the burden of disease. Since 2014, significant enhancements to Georgia's epidemiologic and laboratory capacity have made PPV surveillance and detection possible. In this study, we present information on 27 confirmed cases of PPV infection reported to Georgia's national surveillance system from January 2016 through January 2017.

摘要

在世界许多地区,副痘病毒(PPV)属的病毒引起的感染,包括羊口疮病毒和假性牛痘病毒,在人和动物中都很常见。由于临床医生认识不足、诊断能力不足以及疾病表现相对较轻,这些感染经常被误诊或忽视,这可能导致受影响的个体不去寻求医疗。虽然在患有皮肤损伤的患者中应常规考虑 PPV 感染,特别是那些有职业接触农场动物的患者,但由于它们不被视为严重疾病,因此常常被排除在鉴别诊断之外,从而低估了疾病负担。自 2014 年以来,格鲁吉亚在流行病学和实验室能力方面取得了重大进展,使 PPV 的监测和检测成为可能。在本研究中,我们介绍了 2016 年 1 月至 2017 年 1 月格鲁吉亚国家监测系统报告的 27 例确诊的 PPV 感染病例的信息。

相似文献

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Parapoxvirus Infections in the Country of Georgia: A Case Series.佐治亚国的副痘病毒感染:病例系列。
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引用本文的文献

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A Review on Human Orf: A Neglected Viral Zoonosis.关于人类传染性脓疱病的综述:一种被忽视的病毒性人畜共患病。
Res Rep Trop Med. 2021 Jul 8;12:153-172. doi: 10.2147/RRTM.S306446. eCollection 2021.
2
Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades.过去二十年副痘病毒的基因组特征与进化
Pathogens. 2020 Oct 27;9(11):888. doi: 10.3390/pathogens9110888.

本文引用的文献

1
[Orf nodules and immunosuppression: a case report and review of therapeutics].[羊痘疮结节与免疫抑制:一例病例报告及治疗方法综述]
Rev Med Brux. 2015 Sep-Oct;36(5):439-43.
2
An Investigation of a Cluster of Parapoxvirus Cases in Missouri, Feb-May 2006: Epidemiologic, Clinical and Molecular Aspects.2006 年 2 月至 5 月密苏里州一组副黏液病毒病例的调查:流行病学、临床和分子方面。
Animals (Basel). 2013 Feb 28;3(1):142-57. doi: 10.3390/ani3010142.
3
Human infection with a zoonotic orthopoxvirus in the country of Georgia.格鲁吉亚境内出现人类感染人畜共患正痘病毒的情况。
N Engl J Med. 2015 Mar 26;372(13):1223-30. doi: 10.1056/NEJMoa1407647.
4
Evidence of zoonotic pseudocowpox virus infection from a cattle in Turkey.来自土耳其一头牛的人畜共患假牛痘病毒感染的证据。
Virusdisease. 2014;25(3):381-4. doi: 10.1007/s13337-014-0214-z. Epub 2014 Jun 7.
5
Novel poxvirus infection in 2 patients from the United States.来自美国的两名患者感染新型痘病毒。
Clin Infect Dis. 2015 Jan 15;60(2):195-202. doi: 10.1093/cid/ciu790. Epub 2014 Oct 9.
6
Evidence of local persistence of human anthrax in the country of georgia associated with environmental and anthropogenic factors.与环境和人为因素相关的格鲁吉亚国内人类炭疽局部持续存在的证据。
PLoS Negl Trop Dis. 2013 Sep 5;7(9):e2388. doi: 10.1371/journal.pntd.0002388. eCollection 2013.
7
Specific qPCR assays for the detection of orf virus, pseudocowpox virus and bovine papular stomatitis virus.用于检测口疮病毒、假性牛痘病毒和牛丘疹性口炎病毒的特定 qPCR 检测方法。
J Virol Methods. 2013 Dec;194(1-2):229-34. doi: 10.1016/j.jviromet.2013.08.027. Epub 2013 Sep 12.
8
ORF virus infection in a hunter in Western Austria, presumably transmitted by game.
Acta Derm Venereol. 2014 Mar;94(2):212-4. doi: 10.2340/00015555-1643.
9
Nosocomial outbreak of disseminated orf infection in a burn unit, Gaziantep, Turkey, October to December 2012.2012 年 10 月至 12 月,土耳其加济安泰普一家烧伤病房发生散发性羊痘感染的医院感染暴发。
Euro Surveill. 2013 Mar 14;18(11):20425. doi: 10.2807/ese.18.11.20425-en.
10
Electronic integrated disease surveillance system and pathogen asset control system.电子综合疾病监测系统和病原体资产控制系统。
Onderstepoort J Vet Res. 2012 Jun 20;79(2):455. doi: 10.4102/ojvr.v79i2.455.