Mourek J, Base J, Smídová L, Miková M, Vízek K, Melichar V
Institute of Physiology, Faculty of Medicine, Charles University, Prague.
Physiol Bohemoslov. 1987;36(6):503-10.
The proportion of a wide range of fatty acids was studied in the plasma of 15 healthy newborn infants following a physiological pregnancy and delivery. The same measurements were done in seven healthy mothers (immediately after parturition) and the proportion of fatty acids was analysed in mixed umbilical cord blood (n = 7). The fatty acids were identified by gas chromatography as their methyl esters (FAME). In newborn infants the proportion of saturated fatty acids was found to be 42.3%, of monoene fatty acids 31.3% and of polyene fatty acids 25.4%; type n-6 fatty acids formed 13.9% and n-3 11.1%. The proportion of the various fatty acids in healthy maternal plasma was 37.9% (saturated), 34.4% (monoene) and 25.0% (polyene) respectively; type n-6 fatty acids formed 21.6% and type n-3 only 3.6%. The values in mixed cord blood were 44% (saturated FA), 34.8% (monoene FA) and 20% (polyene FA); group n-6 FA accounted for 17.4% and n-3 for only 2.1%. In the above three series we also described the sequence of the fatty acids present in the largest amounts. This is part of an extensive study, in a large series, of the commonest perinatal risks. We particularly draw attention to the high proportion of long-chain fatty acids (C 22 - C 26) in the plasma of healthy newborn infants.
对15名生理妊娠和分娩后的健康新生儿血浆中的多种脂肪酸比例进行了研究。对7名健康母亲（产后即刻）进行了相同的测量，并分析了混合脐带血（n = 7）中的脂肪酸比例。脂肪酸通过气相色谱法鉴定为其甲酯（FAME）。在新生儿中，饱和脂肪酸的比例为42.3%，单烯脂肪酸为31.3%，多烯脂肪酸为25.4%；n-6型脂肪酸占13.9%，n-3型占11.1%。健康母体血浆中各种脂肪酸的比例分别为37.9%（饱和）、34.4%（单烯）和25.0%（多烯）；n-6型脂肪酸占21.6%，n-3型仅占3.6%。混合脐带血中的值为44%（饱和脂肪酸）、34.8%（单烯脂肪酸）和20%（多烯脂肪酸）；n-6组脂肪酸占17.4%，n-3组仅占2.1%。在上述三个系列中，我们还描述了含量最高的脂肪酸序列。这是对一系列最常见围产期风险进行广泛研究的一部分。我们特别提请注意健康新生儿血浆中长链脂肪酸（C 22 - C 26）的高比例。
