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[奥地利和匈牙利新生儿脐带血中血浆磷脂的脂肪酸水平]

[Fatty acid levels in plasma phospholipids in the cord blood of Austrian and Hungarian newborn infants].

作者信息

Decsi T, Minda H, Burus I, Sárkány I, Volker V

机构信息

Pécsi Orvostudományi Egyetem, Gyermekgyógyászati Klinika.

出版信息

Orv Hetil. 1999 Apr 18;140(16):881-4.

Abstract

Fatty acid composition of plasma phospholipids in venous cord blood of 13 Austrian and 13 Hungarian infants was determined by high resolution capillary gas liquid chromatography. Values of linoleic acid and arachidonic acid [13.69 (12.57, 14.30) versus 19.79 (11.74, 22.83), % weight/weight, median (first and third quartile), Austrian versus Hungarian] did not differ between the two groups. Values of alpha-linolenic acid were slightly higher in Hungarian than in Austrian infants, whereas docosahexaenoic acid values did not differ [3.75 (2.80, 4.05)] versus 4.11 (1.55, 5.19)]. Neither saturated, nor cis monounsaturated fatty acid values differed between the two groups. Values of trans isometric fatty acids were significantly higher in Hungarian than in Austrian infants [total: 0.81 (0.70, 1.10) versus 1.19 (0.92, 1.46) p < 0.01]. Analysis of fatty acid composition of plasma phospholipids in venous cord blood of Austrian and Hungarian infants did not reveal major differences in the availability of essential and long-chain polyunsaturated fatty acids. Significantly higher contribution of trans isometric fatty acids to plasma phospholipids in Hungarian than in Austrian infants indicates higher dietary exposure of pregnant women to trans fatty acids in Hungary.

摘要

采用高分辨率毛细管气液色谱法测定了13名奥地利婴儿和13名匈牙利婴儿脐带血中血浆磷脂的脂肪酸组成。两组之间亚油酸和花生四烯酸的值没有差异[13.69(12.57,14.30)对19.79(11.74,22.83),重量/重量百分比,中位数(第一和第三四分位数),奥地利婴儿对匈牙利婴儿]。匈牙利婴儿α-亚麻酸的值略高于奥地利婴儿,而二十二碳六烯酸的值没有差异[3.75(2.80,4.05)对4.11(1.55,5.19)]。两组之间饱和脂肪酸和顺式单不饱和脂肪酸的值均无差异。匈牙利婴儿反式异构脂肪酸的值显著高于奥地利婴儿[总计:0.81(0.70,1.10)对1.19(0.92,1.46),p<0.01]。对奥地利和匈牙利婴儿脐带血中血浆磷脂的脂肪酸组成分析未发现必需脂肪酸和长链多不饱和脂肪酸的可利用性存在主要差异。匈牙利婴儿反式异构脂肪酸对血浆磷脂的贡献显著高于奥地利婴儿,这表明匈牙利孕妇饮食中反式脂肪酸的暴露量更高。

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