阿根廷布宜诺斯艾利斯一家健康维护组织中的慢性荨麻疹——增加对该疾病全球认知的新数据。
Chronic urticaria in a health maintenance organization of Buenos Aires, Argentina - new data that increase global knowledge of this disease.
作者信息
Parisi Claudio Alberto, Ritchie Carla, Petriz Natalia, Torres Christian Morelo, Gimenez-Arnau Ana
机构信息
Sección de alergia de adultos y pediátrica, Hospital Italiano de Buenos Aires - Buenos Aires, Argentina.
Department of Dermatology. Hospital del Mar. Institut Mar d'Investigacions mèdiques. Universitat Autònoma - Barcelona, Spain.
出版信息
An Bras Dermatol. 2018 Jan-Feb;93(1):76-79. doi: 10.1590/abd1806-4841.20186984.
BACKGROUND
In spite of the frequency of chronic urticaria, there are no epidemiological studies on its prevalence in Argentina.
OBJECTIVE
The objective of this study was to define the prevalence and epidemiological characteristics of chronic urticaria patients in Buenos Aires.
METHODS
The population studied were the members of the Italian Hospital Medical Care Program, a prepaid health maintenance organization located in the urban areas around the Autonomous City of Buenos Aires, Argentina. All patients with diagnosis of chronic urticaria members of the Italian Hospital Medical Care Program, and with at least 12 months of follow up were included in the study. All medical records obtained between January 1st, 2012 and December 31, 2014 were analyzed. The prevalence ratio for chronic urticaria per 100,000 population with 95% CI for December 31, 2014 was calculated. The prevalence rate for the entire population and then discriminated for adults and pediatric patients (less than 18 years old at diagnosis) was assessed.
RESULTS
158,926 members were analyzed. A total of 463 cases of chronic urticaria were identified on prevalence date (68 in pediatrics, 395 in adults), yielding a crude point prevalence ratio of 0.29% (CI 95% 0.26-0.31%). The observed prevalence of chronic urticaria in the adult population was 0.34 % (95% CI 0.31-0.38%), while in pediatrics it was 0.15 % (95% CI 0.11-0.20%).
STUDY LIMITATIONS
the main weakness is that the results were obtained from an HMO and therefore the possibility of selection bias.
CONCLUSIONS
chronic urticaria is a global condition. Its prevalence in Buenos Aires is comparable with other countries.
背景
尽管慢性荨麻疹发病率较高，但阿根廷尚无关于其患病率的流行病学研究。
目的
本研究旨在确定布宜诺斯艾利斯慢性荨麻疹患者的患病率及流行病学特征。
方法
研究对象为意大利医院医疗保健项目的成员，该项目是一家位于阿根廷布宜诺斯艾利斯自治市周边市区的预付健康维护组织。所有被诊断为慢性荨麻疹且属于意大利医院医疗保健项目成员、并至少随访12个月的患者均纳入本研究。对2012年1月1日至2014年12月31日期间获取的所有病历进行分析。计算了2014年12月31日每10万人口中慢性荨麻疹的患病率及95%置信区间。评估了整个人口的患病率，然后区分成人和儿科患者（诊断时年龄小于18岁）的患病率。
结果
共分析了158,926名成员。在患病率统计日共确定463例慢性荨麻疹病例（儿科68例，成人395例），粗点患病率为0.29%（95%置信区间0.26 - 0.31%）。观察到成人慢性荨麻疹患病率为0.34%（95%置信区间0.31 - 0.38%），儿科为0.15%（95%置信区间0.11 - 0.20%）。
研究局限性
主要不足在于结果来自健康维护组织，因此存在选择偏倚的可能性。
结论
慢性荨麻疹是一种全球性疾病。其在布宜诺斯艾利斯的患病率与其他国家相当。
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