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萎缩性结节性皮肤淀粉样变性

Atrophic nodular cutaneous amyloidosis.

作者信息

Jiang Yuan, Kong Qingtao, Hui Yun, Sang Hong

机构信息

Department of Dermatology, NanJing First Hospital, NanJing Medical University - Nanjing, China.

Department of Dermatology, Jinling Hospital, Medical School of Nanjing University - Nanjing, China.

出版信息

An Bras Dermatol. 2018 Jan-Feb;93(1):111-113. doi: 10.1590/abd1806-4841.20186504.

Abstract

Primary cutaneous amyloidosis is limited to the skin without involving any other tissue. Nodular amyloidosis is rare, and atrophic nodular cutaneous amyloidosis is even rarer. We describe the fourth case of atrophic nodular cutaneous amyloidosis by searching PubMed databases. A 52-year-old female presented to our hospital with a 2-year history of orange papules and nodules without subjective symptom on her right abdomen. Review of systems was negative. Atrophic nodular amyloidosis may progress to primary systemic disease in up to 7% of cases. Because our patient had no systemic involvement, she was diagnosed with atrophic nodular cutaneous amyloidosis based on characteristic symptoms and histopathologic examination. Routine follow-up for this patient is necessary to detect any potential disease progression.

摘要

原发性皮肤淀粉样变仅局限于皮肤,不累及任何其他组织。结节性淀粉样变罕见,萎缩性结节性皮肤淀粉样变则更为罕见。我们通过检索PubMed数据库描述了第四例萎缩性结节性皮肤淀粉样变。一名52岁女性因右侧腹部出现橙色丘疹和结节2年且无主观症状前来我院就诊。系统回顾为阴性。高达7%的萎缩性结节性淀粉样变病例可能进展为原发性系统性疾病。由于我们的患者无系统性受累,根据特征性症状和组织病理学检查,她被诊断为萎缩性结节性皮肤淀粉样变。对该患者进行常规随访以检测任何潜在的疾病进展是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7551/5871374/f26132ff04a3/abd-93-01-0111-g01.jpg

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